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Trogocytosis represents a novel mechanism of action of daratumumab in multiple myeloma.

作者信息

Krejcik Jakub, van de Donk Niels W C J

机构信息

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Hematology, Amsterdam, The Netherlands.

出版信息

Oncotarget. 2018 Sep 14;9(72):33621-33622. doi: 10.18632/oncotarget.26098.

Abstract
摘要

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本文引用的文献

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CD38 antibodies in multiple myeloma: back to the future.
Blood. 2018 Jan 4;131(1):13-29. doi: 10.1182/blood-2017-06-740944. Epub 2017 Nov 8.
2
Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab.
Clin Cancer Res. 2017 Dec 15;23(24):7498-7511. doi: 10.1158/1078-0432.CCR-17-2027. Epub 2017 Oct 12.
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Microenvironment drug resistance in multiple myeloma: emerging new players.
Oncotarget. 2016 Sep 13;7(37):60698-60711. doi: 10.18632/oncotarget.10849.
5
CD38 expression and complement inhibitors affect response and resistance to daratumumab therapy in myeloma.
Blood. 2016 Aug 18;128(7):959-70. doi: 10.1182/blood-2016-03-703439. Epub 2016 Jun 15.
6
Daratumumab depletes CD38+ immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma.
Blood. 2016 Jul 21;128(3):384-94. doi: 10.1182/blood-2015-12-687749. Epub 2016 May 24.

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