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酒精使用障碍与结核病治疗:泰国的一项纵向混合方法研究。

Alcohol use disorder and tuberculosis treatment: A longitudinal mixed method study in Thailand.

作者信息

Laprawat Samai, Peltzer Karl, Pansila Wirat, Tansakul Chalermpol

机构信息

Faculty of Public Health, Mahasarakham University, Thailand.

HIV/AIDS/STIs and TB (HAST), Human Sciences Research Council, Department of Research Innovation and Development, University of Limpopo, South Africa.

出版信息

S Afr J Psychiatr. 2017 May 30;23:1074. doi: 10.4102/sajpsychiatry.v23i0.1074. eCollection 2017.

Abstract

OBJECTIVE

The relationship between tuberculosis (TB) treatment and alcohol use disorders over time is under-researched. The aim of this investigation was to study alcohol use and TB medication adherence and its predictors among TB patients over a period of 6 months.

METHODS

A longitudinal investigation was carried out with new TB and TB retreatment patients systematically selected from two hospitals and had screened positive for hazardous or harmful alcohol use in Sisaket Province in Thailand. Alcohol use disorders were measured with Alcohol Use Disorder Identification Test (AUDIT)-C at baseline, 3 months and 6 months.

RESULTS

Of the 295 TB patients who were screened with AUDIT-C, 72 (24.4%) tested positive for hazardous or harmful alcohol use. At 6 months, 72 TB patients had completed the follow-up. At the 6-month follow-up, hazardous or harmful drinking was reduced by 84.7%. Multivariate logistic regression analysis using generalised estimation equation modelling found that alcohol use significantly reduced over time, whereas there was no change in current tobacco use.

CONCLUSION

The prevalence of alcohol use disorders significantly reduced over a period of 6 months.

摘要

目的

结核病(TB)治疗与酒精使用障碍之间随时间变化的关系研究不足。本调查旨在研究6个月期间结核病患者的酒精使用情况、结核病药物治疗依从性及其预测因素。

方法

对从泰国四色菊府两家医院系统选取的新发结核病患者和结核病复治患者进行了一项纵向调查,这些患者在酒精使用障碍识别测试(AUDIT-C)中筛查出有害或危险饮酒呈阳性。在基线、3个月和6个月时使用酒精使用障碍识别测试(AUDIT-C)测量酒精使用障碍。

结果

在接受AUDIT-C筛查的295例结核病患者中,72例(24.4%)有害或危险饮酒检测呈阳性。6个月时,72例结核病患者完成了随访。在6个月的随访中,有害或危险饮酒减少了84.7%。使用广义估计方程模型进行的多变量逻辑回归分析发现,随着时间的推移,酒精使用显著减少,而当前吸烟情况没有变化。

结论

在6个月的时间里,酒精使用障碍的患病率显著降低。

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