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患者在医院药物治疗中的优先排序:评估工具的系统评价。

Patient prioritization for pharmaceutical care in hospital: A systematic review of assessment tools.

机构信息

Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT, United Kingdom.

出版信息

Res Social Adm Pharm. 2019 Jun;15(6):767-779. doi: 10.1016/j.sapharm.2018.09.009. Epub 2018 Sep 20.

Abstract

BACKGROUND

Clinical pharmacy services improve patient safety, outcomes, and care quality; however, UK clinical pharmacy services face limited resources, insufficient capacity, and patients who present with increasingly complex medication regimes and morbidities. These indicate a need for the prioritization of pharmacy services. Several prioritization tools have been developed; however, there has been no comprehensive review of such tools to date.

OBJECTIVE

A systematic review was conducted to provide a structured overview and description of existing assessment tools with a focus on study quality, themes, tool validity, risk factors, and high-risk drug classes.

METHODS

Systematic searches for English-language publications (from 1990 to September 2017) were conducted in Embase, Medline, Scopus, International Pharmaceutical Abstracts, and Web of Science. Papers in the inpatient setting and in which the tool users were pharmacists or pharmacy technicians were included. Data on each study (e.g. aim and design) and the structure of tools (e.g. risk factors) from each included study were extracted by 2 independent reviewers. A descriptive analysis was conducted to summarize these tools along with a thematic analysis of study findings. The quality of each paper was assessed using the Hawker method.

RESULTS

Nineteen studies involving 17 risk assessment tools were included. Most tools were developed in Europe (76.5%) and published in the last 5 years (82%). Most tools (88%) were designed to identify patients at greatest risk of adverse drug reactions, adverse drug events, or medication errors and to guide appropriate pharmaceutical care. Ten out of 17 tools (59%) were validated. None showed a measurable impact on prescription errors or adverse drug events. Keys themes identified from the studies were the positive impact of risk assessment tools on both patient care and provision of pharmacy services as well as the limitations of risk assessment tools.

CONCLUSIONS

Current assessment tools are heterogeneous in their content, targeting diverse patient groups and clinical settings making generalization difficult. However, an underlying theme of all studies was that tools appear to achieve their aim in directing pharmaceutical care to where it is needed most which might provide reassurance and incentive for greater adoption and development of tools across clinical pharmacy services. However, further research is required to measure objectively the impact of tools on patient outcomes and on workforce efficiency so that comparisons can be made between tools.

摘要

背景

临床药学服务可提高患者安全性、治疗效果和护理质量;然而,英国临床药学服务面临着资源有限、能力不足的问题,患者的用药方案也越来越复杂,合并症也越来越多。这表明需要对药学服务进行优先排序。目前已经开发了几种优先排序工具;然而,迄今为止,还没有对这些工具进行全面的综述。

目的

进行了系统评价,以提供现有评估工具的结构化概述和描述,重点关注研究质量、主题、工具有效性、风险因素和高危药物类别。

方法

系统检索了 1990 年至 2017 年 9 月期间发表的英文文献,检索数据库包括 Embase、Medline、Scopus、国际药学文摘和 Web of Science。纳入了住院患者人群中,以及工具使用者为药剂师或药剂技术员的研究。由 2 名独立评审员提取每项研究的相关数据(例如,目的和设计)和工具结构(例如,风险因素)。对这些工具进行了描述性分析,并对研究结果进行了主题分析。使用 Hawker 方法评估了每篇论文的质量。

结果

共纳入 19 项研究,涉及 17 种风险评估工具。大多数工具(76.5%)在欧洲开发,且发表于最近 5 年(82%)。大多数工具(88%)旨在识别发生药物不良反应、药物不良事件或用药错误风险最高的患者,并指导提供适当的药学服务。17 种工具中有 10 种(59%)经过了验证。没有一种工具能够对处方错误或药物不良事件产生可衡量的影响。从研究中得出的关键主题包括风险评估工具对患者护理和药学服务提供的积极影响,以及风险评估工具的局限性。

结论

目前的评估工具在内容上存在差异,针对不同的患者群体和临床环境,难以进行推广。然而,所有研究的一个潜在主题是,这些工具似乎能够实现其目标,即指导药学服务最需要的地方,这可能为在临床药学服务中更广泛地采用和开发这些工具提供信心和激励。但是,还需要进一步研究来客观衡量工具对患者结局和劳动力效率的影响,以便对工具进行比较。

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