Dentistry Area, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
iCBR, Coimbra Institute of Clinical and Biomedical Research, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
J Esthet Restor Dent. 2019 Jan;31(1):26-39. doi: 10.1111/jerd.12420. Epub 2018 Oct 4.
Defects in the maturation stage of amelogenesis result in a normal volume of enamel but insufficient mineralization, called hypomineralization. Molar-incisor hypomineralization (MIH), amelogenesis imperfecta and dental fluorosis (DF) are examples of such defects.
To evaluate the effectiveness of the treatments applied to the different forms of dental hypomineralization.
PubMed, Scopus, Cochrane Library, Web of Science, and Embase were screened. The research was limited to studies published in English, Spanish, and Portuguese, until May 30, 2018. The research question was formulated following the Population, Intervention, Comparison, Outcome strategy. The quality of the methodology of each article was evaluated employing the Cochrane Handbook for Systematic Reviews.
From the initial research, 7895 references were obtained, of which 33 were included in the systematic review. The following treatments were reported: desensitizing and remineralizing products, resin infiltration, restorations, fissure sealants, tooth bleaching, enamel microabrasion and calcium, and vitamins supplements.
Although the results are suggestive, there is a clear need for a greater uniformity of the methodologies, thus allowing for the development of clinical guidelines. Nevertheless, it was possible to identify several effective treatments for teeth with MIH (arginine pastes or fluoride varnishes) and DF (tooth bleaching and/or enamel microabrasion).
Because MIH, amelogenesis imperfecta, and DF are commonly seen in dental daily practice, it is extremely important to analyze the literature regarding its treatment.
成釉细胞成熟阶段的缺陷会导致釉质体积正常但矿化不足,称为矿化不全。磨牙-切牙矿化不全(MIH)、釉质发育不全和氟牙症(DF)就是这种缺陷的例子。
评估应用于不同形式的牙齿矿化不全的治疗方法的有效性。
对 PubMed、Scopus、Cochrane 图书馆、Web of Science 和 Embase 进行筛选。研究仅限于发表于英语、西班牙语和葡萄牙语的研究,截至 2018 年 5 月 30 日。研究问题是根据人群、干预、比较、结果策略制定的。采用 Cochrane 系统评价手册评价每篇文章方法学的质量。
从最初的研究中,获得了 7895 条参考文献,其中 33 条被纳入系统评价。报告了以下治疗方法:脱敏和再矿化产品、树脂渗透、修复、窝沟封闭剂、牙齿漂白、釉质微研磨和钙及维生素补充剂。
尽管结果具有提示性,但显然需要更大程度地统一方法,从而制定临床指南。然而,已经可以确定几种针对 MIH(精氨酸糊剂或氟化物漆)和 DF(牙齿漂白和/或釉质微研磨)的有效治疗方法。
由于 MIH、釉质发育不全和 DF 在口腔日常临床实践中很常见,因此分析有关其治疗的文献极其重要。