From the Centers for Disease Control and Prevention, Atlanta, Georgia. (A.Y.G., P.K.K.).
Ann Intern Med. 2018 Oct 2;169(7):ITC49-ITC64. doi: 10.7326/AITC201810020.
Clostridioides difficile (formerly Clostridium difficile) infection is the most frequently identified health care-associated infection in the United States. C difficile has also emerged as a cause of community-associated diarrhea, resulting in increased incidence of community-associated infection. Clinical illness ranges in severity from mild diarrhea to fulminant colitis and death. Appropriate management of infection requires understanding of the various diagnostic assays and therapeutic options as well as relevant measures to infection prevention. This article provides updated recommendations regarding the prevention, diagnosis, and treatment of incident and recurrent C difficile infection.
艰难梭菌（以前称为艰难梭菌）感染是美国最常见的与卫生保健相关的感染。艰难梭菌也已成为社区相关腹泻的病因，导致社区相关感染的发生率增加。临床疾病的严重程度从轻度腹泻到暴发性结肠炎和死亡不等。适当的感染管理需要了解各种诊断检测和治疗选择以及相关的感染预防措施。本文提供了关于新发和复发性艰难梭菌感染的预防、诊断和治疗的最新建议。
