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[蓝趾综合征作为嗜铬细胞瘤的临床体征]

[Blue toe syndrome as a clinical finding of pheochromocytoma].

作者信息

Mosquera Rey Vicente, Palomo Antequer Carmen, Cienfuegos Basanta Carmen, Zanabili Al-Sibbai Amer, Fidalgo Navarro Alba, Alonso Pérez Manuel

机构信息

Servicio de Angiología y Cirugía Vascular, Hospital Universitario Central de Asturias (HUCA), Oviedo, España. E-mail:

Servicio de Medicina Interna, Hospital Universitario Central de Asturias (HUCA), Oviedo, España.

出版信息

Medicina (B Aires). 2018;78(5):368-371.

Abstract

Pheochromocytomas are tumors that arise from chromaffin cells of the sympathetic nervous system and act by synthesizing and releasing catecholamines. They usually occur between the fourth and fifth decade of life and have a very wide clinical presentation. They occur only in 0.1-0.2% of the hypertensive population and represent a treatable and curable cause of arterial hypertension, as well as other symptoms derived from the uncontrolled secretion of catecholamines. Peripheral arterial ischemia secondary to massive amines release by a pheochromocytoma is a very uncommon condition. Here we report a case of pheochromocytoma manifested as blue finger syndrome in a patient with palpable distal pulses and history of poor blood pressure control despite treatment with two drugs.

摘要

嗜铬细胞瘤是起源于交感神经系统嗜铬细胞的肿瘤,通过合成和释放儿茶酚胺发挥作用。它们通常发生在生命的第四和第五个十年之间,临床表现非常广泛。它们仅在0.1-0.2%的高血压人群中出现,是动脉高血压以及儿茶酚胺分泌不受控制所产生的其他症状的一种可治疗和可治愈的病因。嗜铬细胞瘤大量释放胺导致的外周动脉缺血是一种非常罕见的情况。在此,我们报告一例嗜铬细胞瘤表现为蓝指综合征的病例,该患者远端脉搏可触及,尽管使用了两种药物治疗,但仍有血压控制不佳的病史。

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