Royal Cornwall Hospital NHS Trust, Truro, UK.
Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.
Psychooncology. 2019 Jan;28(1):48-53. doi: 10.1002/pon.4908. Epub 2018 Oct 19.
To investigate the association between body mass index (BMI) and sexual functioning in gynaecologic cancer patients. To determine the association between socio-economic deprivation and sexual functioning.
This is a prospective cohort study on women undergoing surgery for suspected or proven gynaecological cancer between September 2014 and February 2016 in the Royal Cornwall Hospital Trust. Patients were invited to participate by completing the Female Sexual Function Index (FSFI) at three time points: preoperative, 3 months postoperative, and 1 year postoperative. A semiparametric model of the FSFI score was used to establish the association between BMI and sexual functioning.
A total of 257 patients were approached of which 166 patients were included. Fifty-two patients (33.8%) were overweight (BMI, 25-29.9 kg/m ), 44 (28.6%) were obese (BMI, 30-39.9 kg/m ), and a further 20 (13.0%) morbidly obese (BMI ≥ 40 kg/m ). Overweight and obese women reported improved sexual functioning compared with normal-weight women in endometrial, ovarian, and vulvar cancers. Among cervical cancer, worse sexual functioning was seen in women with an increased BMI; however, this was not significant. Younger age was associated with improved sexual function, and sexual functioning was better postoperatively for all patients compared with preoperatively. There was no evidence of relationship between deprivation and sexual functioning in gynaecological cancer patients.
Higher BMI is associated with improved sexual functioning in endometrial, ovarian, and vulvar cancer; however, this was not seen in cervical cancer patients. There is no evidence of correlation between deprivation and sexual functioning.
探讨体重指数（BMI）与妇科癌症患者性功能之间的关系。确定社会经济剥夺与性功能之间的关系。
这是一项针对 2014 年 9 月至 2016 年 2 月在皇家康沃尔医院信托基金接受疑似或确诊妇科癌症手术的女性的前瞻性队列研究。通过在三个时间点（术前、术后 3 个月和术后 1 年）填写女性性功能指数（FSFI）来邀请患者参与。使用 FSFI 评分的半参数模型来确定 BMI 与性功能之间的关系。
共接触了 257 名患者，其中有 166 名患者被纳入。52 名患者（33.8%）超重（BMI，25-29.9kg/m ），44 名患者（28.6%）肥胖（BMI，30-39.9kg/m ），另有 20 名患者（13.0%）病态肥胖（BMI≥40kg/m ）。与体重正常的女性相比，超重和肥胖的女性在子宫内膜癌、卵巢癌和外阴癌中报告了改善的性功能。在宫颈癌中，BMI 增加的女性性功能更差；然而，这并不显著。年龄越小，性功能越好，所有患者术后的性功能均优于术前。在妇科癌症患者中，没有证据表明贫困与性功能之间存在关系。
BMI 较高与子宫内膜癌、卵巢癌和外阴癌患者的性功能改善相关；然而，在宫颈癌患者中并未见到这种情况。没有证据表明贫困与性功能之间存在相关性。
