University of North Carolina at Chapel Hill, School of Nursing, Campus Box 7460, Chapel Hill, North Carolina 27599-7460, United States.
University of North Carolina at Chapel Hill, Gillings School of Global Public Health, Department of Maternal and Child Health, Campus Box 7445, Chapel Hill, North Carolina 27599-7445, United States.
J Diabetes Complications. 2018 Dec;32(12):1148-1152. doi: 10.1016/j.jdiacomp.2018.09.014. Epub 2018 Sep 26.
Diabetes is associated with significant pregnancy complications, which can be further exacerbated by comorbid hypertension. Racial/ethnic differentials in the burden of comorbid hypertension and diabetes among women of reproductive age have not been described.
Using Wave IV of the nationally representative National Longitudinal Study of Adolescent to Adult Health (Add Health), we analyzed survey and biological data from 6576 non-pregnant women who were aged 24-32 in 2007-2008. Hypertension and diabetes were identified by self-report of diagnosis and biological measurements taken during in-home interviews. We used logistic regression models to predict the presence of comorbid hypertension and diabetes and whether each was diagnosed.
Over a third (36.0%) of women with diabetes had comorbid hypertension. Compared to non-Hispanic white women, more non-Hispanic black women had comorbid hypertension and diabetes (adjusted odds ratio (aOR) 5.93, 95% CI 3.84-9.16), and, if comorbid, were less likely to have a diabetes diagnosis (aOR 0.03, 95% CI 0.007-0.1) or hypertension diagnosis (aOR 0.22, 95% CI 0.08-0.65).
Comorbid hypertension and diabetes are more common among non-Hispanic black women and less likely to be diagnosed, signaling disparities threatening maternal and child health among women with diabetes.
糖尿病与重大妊娠并发症相关,而合并症高血压则会进一步加重这些并发症。目前尚未描述育龄期女性中合并症高血压和糖尿病的种族/民族差异。
利用具有全国代表性的青少年至成年健康纵向研究(Add Health)的第四波数据,我们分析了 2007-2008 年期间 6576 名年龄在 24-32 岁之间的非孕妇的调查和生物学数据。高血压和糖尿病是通过诊断自我报告和家庭访谈期间的生物学测量来确定的。我们使用逻辑回归模型预测合并症高血压和糖尿病的存在情况,以及每种疾病的诊断情况。
超过三分之一(36.0%)的糖尿病患者合并患有高血压。与非西班牙裔白人女性相比,更多的非西班牙裔黑人女性患有合并症高血压和糖尿病(调整后的优势比(aOR)为 5.93,95%置信区间(CI)为 3.84-9.16),如果合并症存在,则更不可能被诊断出患有糖尿病(aOR 为 0.03,95%CI 为 0.007-0.1)或高血压(aOR 为 0.22,95%CI 为 0.08-0.65)。
非西班牙裔黑人女性中合并症高血压和糖尿病更为常见,且不太可能被诊断出来,这表明存在威胁糖尿病女性母婴健康的差异。