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引入围手术期和处方药师服务以改善药物管理。

Improved Medication Management With Introduction of a Perioperative and Prescribing Pharmacist Service.

机构信息

Pharmacy Department, Frankston Hospital, Peninsula Health, Frankston, Victoria, Australia.

Department of Anaesthesia, Frankston Hospital, Peninsula Health, Frankston, Victoria, Australia.

出版信息

J Pharm Pract. 2020 Jun;33(3):299-305. doi: 10.1177/0897190018804961. Epub 2018 Oct 8.

Abstract

BACKGROUND

The medication lists in pre-admission clinic (PAC) questionnaires completed by patients prior to surgery are often inaccurate, potentially leading to medication errors during hospitalization. Studies have shown pharmacists are more accurate when obtaining a medication history and transcribing prescription orders, thereby reducing errors.

OBJECTIVE

To evaluate the impact of a PeRiopErative and Prescribing (PREP) pharmacist on postoperative medication management.

METHODS

A randomized prospective interventional study enrolled elective surgery patients at high risk for medication misadventure to receive PREP pharmacy service or usual care (control group). A best possible medication history (BPMH) was obtained by the PREP pharmacist and was available to surgical staff on admission. The PREP pharmacist also prepared discharge prescriptions for their patients. The primary outcomes for the study were accuracy of BPMH and discharge prescriptions compared to usual care. The study was powered to 80% with 2-tailed significance α of .05.

RESULTS

The medication history in the PREP pharmacist group had fewer errors than the control group: 9% (5/53) versus 96% (49/51; < .001). Discharge prescriptions prepared by the PREP pharmacist had fewer errors than control group: 25% versus 78% ( < .001). Significantly, more PREP pharmacist patients received a discharge summary with a complete medication list: 75% versus 33% ( = .001). Inpatient prescribing was more accurate in the PREP pharmacist patients: 0.64 versus 1.31 errors per patient ( = .047).

CONCLUSION

Inclusion of the PREP pharmacist role in the elective surgery multidisciplinary team improved the accuracy of medication histories, inpatient prescribing, and discharge prescriptions for patients at high risk of medication misadventure.

摘要

背景

患者在手术前于预入院诊所(PAC)问卷中填写的用药清单往往不准确,这可能导致住院期间用药错误。研究表明,药师在获取用药史和转录处方医嘱时更为准确,从而减少错误。

目的

评估围手术期和处方(PREP)药师对术后用药管理的影响。

方法

一项随机前瞻性干预研究招募了择期手术中易发生用药差错的高风险患者,他们接受 PREP 药学服务或常规护理(对照组)。PREP 药师获取最佳可能的用药史(BPMH),并在入院时提供给外科医护人员。PREP 药师还为患者准备出院处方。该研究的主要结局是与常规护理相比,BPMH 和出院处方的准确性。该研究的功效为 80%,双侧显著性 α 为.05。

结果

PREP 药师组的用药史错误少于对照组:9%(5/53)比 96%(49/51;<.001)。PREP 药师组准备的出院处方错误少于对照组:25%比 78%(<.001)。更重要的是,PREP 药师组的患者中有更多人收到了一份包含完整用药清单的出院小结:75%比 33%(=.001)。PREP 药师组患者的住院内处方更准确:每位患者 0.64 比 1.31 个错误(=.047)。

结论

将 PREP 药师角色纳入择期手术多学科团队,提高了高用药风险患者的用药史、住院内处方和出院处方的准确性。

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