Aagaard Mark Faurholt, Khayyami Yasmine, Hansen Frank Bohn, Tofft Hans Peter, Nordling Jørgen
a Department of Urology at Roskilde Hospital , Roskilde , Denmark.
b Department of Urology at Herlev Hospital , University of Copenhagen , Herlev , Denmark.
Scand J Urol. 2018 Oct-Dec;52(5-6):448-452. doi: 10.1080/21681805.2018.1517823. Epub 2018 Oct 9.
Awareness of prostate cancer is growing in the Western population, and an increasing number of patients are being referred to prostate surgery. This is a significant contributor to male stress urinary incontinence (SUI). Implantation of an artificial sphincter (AUS) is considered the gold standard treatment of SUI. This study investigates the role of minimally invasive treatment with the Argus sling in a heterogenic hard-to-treat patient group.
The study was a retrospective follow-up study with patients as their own controls. Forty-one patients were enrolled and treated with the Argus sling. Patients enrolled had persisting SUI after prostate surgery for more than 12 months, despite conservative treatment. The pre-operative daily usage of pads and the 24 hours urinary leakage were compared to the post-operative findings. The primary goal was to achieve complete continence or a reduction of more than 50% in pad usage or urinary leakage.
In total, 71% of the 41 patients enrolled met our primary objective. Complete continence was obtained in 56%, and a reduction of 50% or more was obtained in an additional 15%.
This study has reproduced continence rates seen in previous studies, but in the hard-to-treat patients with urgency or formerly failed surgery, the continence rate was found to be inferior. The AUS has produced similar results and must still be considered the gold standard treatment of SUI, but the Argus sling is an alternative for patients who want a passive system or for patients not suitable for AUS.
在西方人群中,对前列腺癌的认识正在提高,越来越多的患者被转诊至前列腺手术。这是男性压力性尿失禁(SUI)的一个重要原因。人工括约肌(AUS)植入被认为是SUI的金标准治疗方法。本研究调查了Argus吊带微创治疗在异质性难治性患者群体中的作用。
本研究是一项以患者自身为对照的回顾性随访研究。41名患者入组并接受了Argus吊带治疗。入组患者在前列腺手术后尽管接受了保守治疗,但仍持续存在SUI超过12个月。将术前每日使用尿垫情况和24小时尿失禁情况与术后结果进行比较。主要目标是实现完全控尿或尿垫使用量或尿失禁量减少超过50%。
在41名入组患者中,总计71%达到了我们的主要目标。56%的患者实现了完全控尿,另有15%的患者尿垫使用量或尿失禁量减少了50%或更多。
本研究重现了先前研究中的控尿率,但在伴有尿急或既往手术失败的难治性患者中,控尿率较低。AUS产生了类似的结果,仍必须被视为SUI的金标准治疗方法,但Argus吊带对于想要被动系统的患者或不适合AUS的患者来说是一种替代选择。