Suppr超能文献

术中损伤快速评估预测指标(RAPID)评分:一种用于高级别髋臼盂唇撕裂的临床预测模型。

The Rapidly Assessed Predictor of Intraoperative Damage (RAPID) Score: An In-Clinic Predictive Model for High-Grade Acetabular Chondrolabral Disruption.

作者信息

Hevesi Mario, Hartigan David E, Wu Isabella T, Wyles Cody C, Desai Vishal S, van Wijnen Andre J, Saris Daniel B F, Levy Bruce A, Krych Aaron J

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Department of Orthopedic Surgery and Sports Medicine, Mayo Clinic, Phoenix, Arizona, USA.

出版信息

Orthop J Sports Med. 2018 Oct 3;6(10):2325967118799068. doi: 10.1177/2325967118799068. eCollection 2018 Oct.

Abstract

BACKGROUND

The preoperative assessment of cartilage lesions is critical to surgical planning and decision making. The accurate radiographic determination of acetabular cartilage damage has remained elusive for modern imaging modalities, including magnetic resonance imaging (MRI) and magnetic resonance arthrography (MRA). While risk factors have been individually described, no multivariable system exists for predicting high-grade cartilage damage.

PURPOSE

To determine the preoperative predictors of grade 3 to 4 acetabular labrum articular disruption (ALAD) lesions.

STUDY DESIGN

Case-control study; Level of evidence, 3. Cohort study (diagnosis); Level of evidence, 1.

METHODS

Retrievable radiographs were reviewed from primary hip arthroscopic procedures performed at 2 high-volume institutions between December 2007 and April 2017. The predictive value of demographic and radiographic factors for the intraoperative documentation of ALAD grade 3 to 4 damage was analyzed and entered into a multivariable model, and a statistically guided scoring system for the damage risk was created using the Akaike information criterion. The scoring system was then prospectively validated on 167 patients who underwent primary hip arthroscopy between April 2017 and February 2018.

RESULTS

A total of 652 primary hip arthroscopic procedures in 614 patients (390 female, 224 male; mean age, 33.2 ± 12.5 years; mean body mass index, 26.9 ± 5.5 kg/m) from 2007 to 2017 were analyzed. Male sex (odds ratio [OR], 3.11; < .01), age ≥35 years (OR, 1.96; < .01), cam morphology (alpha angle >55°) (OR, 2.96; < .01), and Tönnis grade 1 to 2 (grade 1: OR, 4.14; < .01, and grade 2: OR, 9.29; < .01) were univariate risk factors for intraoperatively documented high-grade damage. A multivariable scoring system, the Rapidly Assessed Predictor of Intraoperative Damage (RAPID) score (0-5 points), was generated based on sex, Tönnis grade, and cam morphology. Patients with increasing RAPID scores had an increasing risk of damage, with a 10.5% risk for those with 0 points and an 88.0% risk for those with 5 points ( < .01). The area under the curve was 0.75 for the study group and 0.76 for the validation group ( = .94).

CONCLUSION

While preoperative MRI has diagnostic value for hip arthroscopic surgery, the RAPID score provides added benefit as a readily employable, in-clinic system for predicting high-grade cartilage damage. The discriminatory value of the RAPID score compares favorably with previous MRI and MRA studies. This information will help the clinician and patient plan for high-grade damage and identify potential targets for cartilage treatment.

摘要

背景

软骨损伤的术前评估对于手术规划和决策至关重要。对于包括磁共振成像(MRI)和磁共振关节造影(MRA)在内的现代成像方式而言,准确通过影像学确定髋臼软骨损伤一直难以实现。虽然已分别描述了一些风险因素,但尚无用于预测高级别软骨损伤的多变量系统。

目的

确定术前3至4级髋臼唇关节破坏(ALAD)损伤的预测因素。

研究设计

病例对照研究;证据等级,3。队列研究(诊断);证据等级,1。

方法

回顾了2007年12月至2017年4月在2家大型机构进行的初次髋关节镜手术的可检索X线片。分析人口统计学和影像学因素对术中记录的3至4级ALAD损伤的预测价值,并将其纳入多变量模型,使用赤池信息准则创建损伤风险的统计指导评分系统。然后,对2017年4月至2018年2月期间接受初次髋关节镜检查的167例患者进行前瞻性验证。

结果

分析了2007年至2017年期间614例患者(390例女性,224例男性;平均年龄33.2±12.5岁;平均体重指数26.9±5.5kg/m)的652例初次髋关节镜手术。男性(优势比[OR],3.11;P<0.01)、年龄≥35岁(OR,1.96;P<0.01)、凸轮形态(α角>55°)(OR,2.96;P<0.01)和Tönnis 1至2级(1级:OR,4.14;P<0.01,2级:OR,9.29;P<0.01)是术中记录的高级别损伤的单变量风险因素。基于性别、Tönnis分级和凸轮形态生成了一个多变量评分系统,即术中损伤快速评估预测器(RAPID)评分(0至5分)。RAPID评分增加的患者损伤风险增加,评分为0分的患者风险为10.5%,评分为5分的患者风险为88.0%(P<0.01)。研究组曲线下面积为0.75,验证组为0.76(P=0.94)。

结论

虽然术前MRI对髋关节镜手术具有诊断价值,但RAPID评分作为一种易于在临床应用的预测高级别软骨损伤的系统具有额外的优势。RAPID评分的鉴别价值与先前的MRI和MRA研究相比具有优势。这些信息将有助于临床医生和患者针对高级别损伤进行规划,并确定软骨治疗的潜在靶点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8177/6170967/b2f801661e43/10.1177_2325967118799068-fig2.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验