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先天性巨细胞病毒预防、意识和政策建议 - 范围界定研究。

Congenital Cytomegalovirus Prevention, Awareness and Policy Recommendations - A Scoping Study.

机构信息

University of Notre Damn Australia, Sydney Campus, School of Medicine, Sydney, NSW, Australia

Cerebral Palsy Alliance, The University of Sydney, Sydney, NSW, Australia

出版信息

Infect Disord Drug Targets. 2020;20(3):291-302. doi: 10.2174/1871526518666181009093725.

Abstract

BACKGROUND

Congenital cytomegalovirus (cCMV) is known to cause childhood deafness, neurodevelopmental disability and death. Simple hygiene precautions are effective in reducing maternal risk of CMV infection.

OBJECTIVE

To review i) awareness of CMV infection and available primary prevention strategies both in the community and amongst health professionals ii) available cCMV information sources in the literature, grey literature and published professional guidelines.

METHODS

Scoping study to i) identify literature pertaining to cCMV awareness amongst parents and health professionals using MedLine and CINAHL databases via EBSCO ii) review one high income country's guidelines and recommendations regarding cCMV infection and pregnancy (example country Australia) iii) grey literature for parental information.

RESULTS

Worldwide awareness of cCMV and of available prevention strategies amongst women and health professionals are poor. Findings internationally suggest at least half of maternity care health professionals do not routinely provide advice to women regarding simple hygiene precautions that can reduce their risk of infection during pregnancy. Though information resources regarding cCMV are available, they are frequently not included within general healthy pregnancy advice and require individuals to search for 'congenital cytomegalovirus'.

CONCLUSION

cCMV is a preventable cause of serious congenital disability and death. Prevention opportunities are being missed because most women are not aware of cCMV or how to reduce their risk of infection in pregnancy, in part due to poor health professional awareness. New strategies to disseminate cCMV information to the community and to support health professionals to embed cCMV advice within routine pregnancy counselling is required.

摘要

背景

先天性巨细胞病毒(cCMV)已知可导致儿童耳聋、神经发育障碍和死亡。简单的卫生预防措施可有效降低母体 CMV 感染风险。

目的

回顾 i)社区和卫生专业人员对 CMV 感染的认识,以及现有的初级预防策略;ii)文献、灰色文献和已发表专业指南中 cCMV 信息来源。

方法

采用范围界定研究,通过 EBSCO 的 MedLine 和 CINAHL 数据库, i)确定有关父母和卫生专业人员对 cCMV 认识的文献;ii)审查一个高收入国家(以澳大利亚为例)有关 cCMV 感染和妊娠的指南和建议;iii)评估针对父母的灰色文献。

结果

全世界范围内,妇女和卫生专业人员对 cCMV 及其现有预防策略的认识都很差。国际研究结果表明,至少有一半的产科保健卫生专业人员没有向妇女常规提供关于简单卫生预防措施的建议,这些措施可以降低她们在怀孕期间感染的风险。虽然有关于 cCMV 的信息资源,但它们通常不包含在一般的健康妊娠建议中,需要个人搜索“先天性巨细胞病毒”。

结论

cCMV 是一种可预防的严重先天性残疾和死亡原因。由于大多数妇女不了解 cCMV 或如何降低其怀孕期间感染的风险,部分原因是卫生专业人员认识不足,因此错过了预防机会。需要向社区传播 cCMV 信息并支持卫生专业人员将 cCMV 建议纳入常规妊娠咨询的新策略。

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