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家族性淀粉样多神经病患者心脏的锝-99m焦磷酸盐单光子发射计算机断层扫描

Technetium-99m pyrophosphate single-photon emission computed tomography of the heart in familial amyloid polyneuropathy.

作者信息

Karp K, Näslund U, Backman C, Eriksson P

出版信息

Int J Cardiol. 1987 Mar;14(3):365-9. doi: 10.1016/0167-5273(87)90209-9.

DOI:10.1016/0167-5273(87)90209-9
PMID:3030945
Abstract

A patient with familial amyloid polyneuropathy and congestive heart failure underwent myocardial imaging using technetium-99m pyrophosphate. Planar scintigraphy showed an intense, diffuse biventricular uptake of the radiotracer. Single-photon emission computed tomography demonstrated an unevenly distributed uptake of the isotope. The greatest activity corresponded to regions with marked echocardiographic changes. Emission tomography may aid in assessing the degree and distribution of the infiltrative lesions in cardiac amyloidosis.

摘要

一名患有家族性淀粉样多神经病和充血性心力衰竭的患者接受了锝-99m焦磷酸盐心肌显像。平面闪烁扫描显示放射性示踪剂在双心室有强烈、弥漫性摄取。单光子发射计算机断层扫描显示同位素摄取分布不均。最大活性对应于超声心动图有明显变化的区域。发射断层扫描可能有助于评估心脏淀粉样变性中浸润性病变的程度和分布。

相似文献

1
Technetium-99m pyrophosphate single-photon emission computed tomography of the heart in familial amyloid polyneuropathy.家族性淀粉样多神经病患者心脏的锝-99m焦磷酸盐单光子发射计算机断层扫描
Int J Cardiol. 1987 Mar;14(3):365-9. doi: 10.1016/0167-5273(87)90209-9.
2
[A case of familial amyloid polyneuropathy demonstrating marked myocardial uptake of technetium-99m-pyrophosphate].
Nihon Naika Gakkai Zasshi. 1985 Jun;74(6):774-9. doi: 10.2169/naika.74.774.
3
[Cardiac involvement in systemic amyloidosis: myocardial scintigraphic evaluation].[系统性淀粉样变的心脏受累:心肌闪烁显像评估]
J Cardiogr. 1985 Mar;15(1):163-80.
4
Early identification of amyloid heart disease by technetium-99m-pyrophosphate scintigraphy: a study with familial amyloid polyneuropathy.通过锝-99m-焦磷酸盐闪烁扫描术早期识别淀粉样心脏病:一项关于家族性淀粉样多神经病的研究。
Am Heart J. 1987 Mar;113(3):654-62. doi: 10.1016/0002-8703(87)90703-4.
5
[Diagnostic significance of technetium-99m-pyrophosphate, technetium-99m-methylene diphosphonate and gallium-67-citrate scintigraphy in amyloid heart disease--a study with AL amyloidosis and familial amyloid polyneuropathy].[锝-99m-焦磷酸盐、锝-99m-亚甲基二膦酸盐和镓-67-柠檬酸盐闪烁扫描术在淀粉样心脏病中的诊断意义——一项关于AL淀粉样变性和家族性淀粉样多神经病的研究]
Nihon Naika Gakkai Zasshi. 1986 Jan;75(1):1-8. doi: 10.2169/naika.75.1.
6
[Technetium-99m-pyrophosphate single photon emission computed tomography of the heart in familial amyloid polyneuropathy: comparison with thallium-201 myocardial scintigraphy--a case report].[家族性淀粉样多神经病患者心脏的锝-99m焦磷酸盐单光子发射计算机断层扫描:与铊-201心肌闪烁扫描术的比较——病例报告]
Kaku Igaku. 1988 Oct;25(10):1117-23.
7
Non-invasive assessment of the presence and severity of cardiac amyloidosis. A study in familial amyloidosis with polyneuropathy by cross sectional echocardiography and technetium-99m pyrophosphate scintigraphy.心脏淀粉样变性的存在及严重程度的无创评估。一项通过横断面超声心动图和锝-99m焦磷酸盐闪烁扫描术对家族性淀粉样变性伴多神经病进行的研究。
Br Heart J. 1984 Sep;52(3):321-6. doi: 10.1136/hrt.52.3.321.
8
[Noninvasive diagnosis of cardiac involvement by technetium-99m-pyrophosphate (Tc-99m PYP) myocardial scintigraphy in 2 cases of familial amyloid polyneuropathy and 1 case of secondary amyloidosis].[99m锝焦磷酸盐(Tc-99m PYP)心肌闪烁显像对2例家族性淀粉样多神经病和1例继发性淀粉样变性心脏受累的无创诊断]
Kaku Igaku. 1989 Dec;26(12):1537-43.
9
Sensitivity of technetium-99m-pyrophosphate scintigraphy in diagnosing cardiac amyloidosis.锝-99m焦磷酸盐闪烁扫描术在诊断心脏淀粉样变性中的敏感性。
Am J Cardiol. 1983 Mar 1;51(5):826-30. doi: 10.1016/s0002-9149(83)80140-4.
10
Cardiac technetium-99m pyrophosphate scintigraphy in familial amyloidosis.
Am J Cardiol. 1984 Nov 1;54(8):1150-1. doi: 10.1016/s0002-9149(84)80170-8.

引用本文的文献

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Estimating cancer risk from Tc pyrophosphate imaging for transthyretin cardiac amyloidosis.用 Tc 焦磷酸盐成像估算转甲状腺素蛋白心脏淀粉样变性的癌症风险。
J Nucl Cardiol. 2020 Feb;27(1):215-224. doi: 10.1007/s12350-018-1307-7. Epub 2018 May 30.
2
Standardization of Technetium pyrophosphate imaging methodology to diagnose TTR cardiac amyloidosis.标准化焦磷酸锝技术成像方法以诊断 TTR 心脏淀粉样变性。
J Nucl Cardiol. 2018 Feb;25(1):181-190. doi: 10.1007/s12350-016-0610-4. Epub 2016 Aug 31.
3
(99m)Tc-pyrophosphate scintigraphy for differentiating light-chain cardiac amyloidosis from the transthyretin-related familial and senile cardiac amyloidoses.
(99m)Tc-焦磷酸盐闪烁显像术鉴别轻链型心脏淀粉样变性与转甲状腺素蛋白相关家族性和老年性心脏淀粉样变性。
Circ Cardiovasc Imaging. 2013 Mar 1;6(2):195-201. doi: 10.1161/CIRCIMAGING.112.000132. Epub 2013 Feb 11.
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Nuclear imaging in cardiac amyloidosis.心脏淀粉样变的核成像
Eur J Nucl Med Mol Imaging. 2009 Apr;36(4):702-14. doi: 10.1007/s00259-008-1037-1. Epub 2009 Jan 21.