Department for Visceral Surgery and Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.
Adv Ther. 2018 Nov;35(11):1729-1734. doi: 10.1007/s12325-018-0797-7. Epub 2018 Oct 16.
Liver transplantation has become a highly standardized, acceptable option for selected patients with end-stage liver disease and/or hepatocellular carcinoma in the setting of cirrhosis. Both conditions are associated with loss of skeletal muscle mass (sarcopenia) and physical deconditioning. Both conditions result in a dramatic decrease in the patients' quality of life, negatively impacting on the pre- and post-transplant prognosis. In this context, awareness of the advantages of physical activity in both the pre- and post-transplant setting is key. However, the importance of regular, individualized and patient-adapted physical activity is still understudied and underestimated. This article describes a three-sided perspective on the importance of physical activity in the setting of liver transplantation, including a patient's, transplant surgeon's and hepatologist's point of view.
肝移植已成为肝硬化背景下终末期肝病和/或肝细胞癌患者的一种高度标准化、可接受的选择。这两种情况都与骨骼肌质量(肌肉减少症)和身体适应能力下降有关。这两种情况都会导致患者的生活质量急剧下降,对移植前和移植后的预后产生负面影响。在这种情况下,认识到体力活动在移植前和移植后的优势是关键。然而,定期、个体化和患者适应的体力活动的重要性仍未得到充分研究和低估。本文从患者、移植外科医生和肝病学家的角度描述了体力活动在肝移植中的重要性的三面观点。