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肝移植中的体力活动:患者和医生的经验。

Physical Activity in Liver Transplantation: A Patient's and Physicians' Experience.

机构信息

Department for Visceral Surgery and Medicine, Bern University Hospital and University of Bern, Bern, Switzerland.

出版信息

Adv Ther. 2018 Nov;35(11):1729-1734. doi: 10.1007/s12325-018-0797-7. Epub 2018 Oct 16.

DOI:10.1007/s12325-018-0797-7
PMID:30328060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6223989/
Abstract

Liver transplantation has become a highly standardized, acceptable option for selected patients with end-stage liver disease and/or hepatocellular carcinoma in the setting of cirrhosis. Both conditions are associated with loss of skeletal muscle mass (sarcopenia) and physical deconditioning. Both conditions result in a dramatic decrease in the patients' quality of life, negatively impacting on the pre- and post-transplant prognosis. In this context, awareness of the advantages of physical activity in both the pre- and post-transplant setting is key. However, the importance of regular, individualized and patient-adapted physical activity is still understudied and underestimated. This article describes a three-sided perspective on the importance of physical activity in the setting of liver transplantation, including a patient's, transplant surgeon's and hepatologist's point of view.

摘要

肝移植已成为肝硬化背景下终末期肝病和/或肝细胞癌患者的一种高度标准化、可接受的选择。这两种情况都与骨骼肌质量(肌肉减少症)和身体适应能力下降有关。这两种情况都会导致患者的生活质量急剧下降,对移植前和移植后的预后产生负面影响。在这种情况下,认识到体力活动在移植前和移植后的优势是关键。然而,定期、个体化和患者适应的体力活动的重要性仍未得到充分研究和低估。本文从患者、移植外科医生和肝病学家的角度描述了体力活动在肝移植中的重要性的三面观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c8f/6223989/e826ed09f129/12325_2018_797_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c8f/6223989/15c587fa5eb6/12325_2018_797_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c8f/6223989/e826ed09f129/12325_2018_797_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c8f/6223989/15c587fa5eb6/12325_2018_797_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c8f/6223989/e826ed09f129/12325_2018_797_Fig2_HTML.jpg

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本文引用的文献

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Physical frailty after liver transplantation.肝移植后的身体虚弱。
Am J Transplant. 2018 Aug;18(8):1986-1994. doi: 10.1111/ajt.14675. Epub 2018 Mar 13.
2
Exercise and physical activity for patients with end-stage liver disease: Improving functional status and sarcopenia while on the transplant waiting list.终末期肝病患者的运动和体育锻炼:改善等待肝移植期间的功能状态和肌肉减少症。
Liver Transpl. 2018 Jan;24(1):122-139. doi: 10.1002/lt.24958.
3
Personalised Prehabilitation in High-risk Patients Undergoing Elective Major Abdominal Surgery: A Randomized Blinded Controlled Trial.
肝移植后的衰弱:一个复杂的未被探索的问题。
J Clin Med. 2024 Aug 2;13(15):4537. doi: 10.3390/jcm13154537.
4
Metabolic Disorders in Liver Transplant Recipients: The State of the Art.肝移植受者的代谢紊乱:最新进展
J Clin Med. 2024 Feb 9;13(4):1014. doi: 10.3390/jcm13041014.
5
Physical activity in liver transplant recipients: a large multicenter study.肝移植受者的体力活动:一项大型多中心研究。
Intern Emerg Med. 2024 Mar;19(2):343-352. doi: 10.1007/s11739-023-03474-7. Epub 2023 Nov 20.
6
Exercise interventions for adults after liver transplantation.肝移植术后成人的运动干预措施。
Cochrane Database Syst Rev. 2023 May 19;5(5):CD013204. doi: 10.1002/14651858.CD013204.pub2.
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Impact of biliary complications on quality of life in live-donor liver transplant recipients.胆道并发症对活体肝移植受者生活质量的影响。
World J Hepatol. 2021 Oct 27;13(10):1405-1416. doi: 10.4254/wjh.v13.i10.1405.
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Physical Function, Physical Activity, and Quality of Life After Liver Transplantation.肝移植后的身体机能、身体活动和生活质量。
Liver Transpl. 2020 May;26(5):702-708. doi: 10.1002/lt.25742.
择期腹部大手术高危患者的个性化术前康复:一项随机双盲对照试验
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