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用于肾缝合术的滑夹技术可改善开放性部分肾切除术的围手术期结局。

Sliding-clip technique for renorrhaphy improves perioperative outcomes of open partial nephrectomy.

作者信息

Crestani Alessandro, Giannarini Gianluca, Rossanese Marta, Calandriello Mattia, Palumbo Vito, Valotto Claudio, Ficarra Vincenzo

机构信息

a Urology Unit , Academic Medical Centre Hospital 'Santa Maria della Misericordia' , Udine , Italy.

b Department of Human and Pediatric Pathology 'Gaetano Barresi'; Urologic Section , University of Messina , Messina , Italy.

出版信息

Scand J Urol. 2018 Oct-Dec;52(5-6):401-406. doi: 10.1080/21681805.2018.1513066. Epub 2018 Oct 19.

Abstract

INTRODUCTION

the aim of this work is to assess whether renorrhaphy with the sliding-clip technique improves perioperative and early functional outcomes compared with traditional renorrhaphy in a contemporary series of patients undergoing open partial nephrectomy (PN).

MATERIAL AND METHODS

A single-center single-surgeon cohort of 107 consecutive patients treated with open PN between July 2013 and March 2017 was analyzed. A study group of 48 patients undergoing renorrhaphy with the sliding-clip technique was compared with a control group of 59 patients receiving traditional renorrhaphy. Outcome measures were operative room (OR) time, warm ischemia time (WIT), estimated blood loss (EBL), rate of overall 90-day postoperative complications, and percentage change in estimated glomerular filtration rate (PCE) > 10% and >20% 1 month postoperatively.

RESULTS

OR time (p = 0.02), WIT (p = 0.01) and EBL (p < 0.001) were significantly lower in the study versus control group. Overall 90-day postoperative complications were observed in 8 (16.7%) versus 21 (35.7%) patients in the study versus control group (p = 0.02). PCE > 10% and >20% 1 month postoperatively were observed in approximately 40% and 20% of patients, respectively, with no significant differences between groups. On multivariable analysis, a sliding-clip technique was an independent predictor of WIT >20 min and/or EBL >500 ml (OR 0.238, 95%CI 0.074-0.767; p = 0.01) and overall 90-day postoperative complications (OR 0.360, 95%CI 0.151-0.856; p = 0.02).

CONCLUSIONS

In patients undergoing open PN, renorrhaphy with the sliding-clip technique was associated with better intraoperative and postoperative outcomes compared with traditional renorrhaphy. No significant differences were observed in terms of early renal function change.

摘要

引言

本研究旨在评估在当代一系列接受开放性部分肾切除术(PN)的患者中,与传统肾缝合术相比,滑动夹技术进行肾缝合术是否能改善围手术期和早期功能结局。

材料与方法

分析了2013年7月至2017年3月期间由同一中心的同一位外科医生连续治疗的107例行开放性PN的患者队列。将48例行滑动夹技术肾缝合术的患者研究组与59例行传统肾缝合术的患者对照组进行比较。观察指标包括手术室(OR)时间、热缺血时间(WIT)估计失血量(EBL)、术后90天总体并发症发生率以及术后1个月估计肾小球滤过率(PCE)变化>10%和>20%的百分比。

结果

研究组的OR时间(p = 0.02)、WIT(p = 0.01)和EBL(p < 0.001)显著低于对照组。研究组和对照组分别有8例(16.7%)和21例(35.7%)患者出现术后90天总体并发症(p = 0.02)。术后1个月PCE>10%和>20%的患者分别约为40%和20%,两组之间无显著差异。多变量分析显示,滑动夹技术是WIT>20分钟和/或EBL>500毫升(OR 0.238,95%CI 0.074 - 0.767;p = 0.01)以及术后90天总体并发症(OR 0.360,95%CI 0.151 - 0.856;p = 0.02)的独立预测因素。

结论

在接受开放性PN的患者中,与传统肾缝合术相比,滑动夹技术进行肾缝合术与更好的术中和术后结局相关。在早期肾功能变化方面未观察到显著差异。

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