多不饱和脂肪酸食物频率问卷在透析终末期肾病患者中的验证。
Polyunsaturated fatty acid food frequency questionnaire validation in people with end stage renal disease on dialysis.
机构信息
School of Medicine, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, Australia.
National Institute for Applied Statistics Research Australia, School of Mathematics and Applied Statistics, University of Wollongong, Wollongong, New South Wales, Australia.
出版信息
Nutr Diet. 2020 Feb;77(1):131-138. doi: 10.1111/1747-0080.12483. Epub 2018 Oct 19.
AIM
To validate the polyunsaturated food frequency questionnaire (PUFA FFQ) and test for reproducibility in people with end stage renal disease on dialysis treatment.
METHODS
Participants (n = 32) completed the PUFA FFQ and three 24-hour recalls. Erythrocyte samples (n = 29) were used for erythrocyte fatty acid analysis. The triangular relationship between the PUFA FFQ, 24-hour recalls and the biomarker was assessed using the method of triads. Agreement between the two dietary methods was also assessed using Bland-Altman plots and classification by quintiles. Reproducibility was tested on a subset of the group (n = 8).
RESULTS
The PUFA FFQ was a valid measure of all PUFA except for docosapentaenoic acid (DPA) and arachidonic acid (AA). Strong validity coefficients were found for n-3 long-chain PUFA (LCPUFA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) of 0.914 (95% CI: 0.665, 0.997) and 0.889 (95% CI: 0.706, 0.994), respectively. In the Bland-Altman plots 91-100% of observations fell between the limits of agreement for all PUFA. There were significant correlations between the initial FFQ and the repeat FFQ for all PUFA except DPA and AA.
CONCLUSIONS
The PUFA FFQ is a valid tool for assessing PUFA intake in people with end stage renal disease.
目的
验证多不饱和脂肪酸食物频率问卷（PUFAFFQ）在接受透析治疗的终末期肾病患者中的可重复性。
方法
参与者（n=32）完成了 PUFAFFQ 和三份 24 小时回忆。红细胞样本（n=29）用于红细胞脂肪酸分析。使用三联体方法评估 PUFAFFQ、24 小时回忆和生物标志物之间的三角关系。还使用 Bland-Altman 图和五分位数分类评估两种饮食方法之间的一致性。对小组中的一部分（n=8）进行了可重复性测试。
结果
PUFAFFQ 是所有 PUFA（除二十二碳五烯酸（DPA）和花生四烯酸（AA）外）的有效测量方法。n-3 长链多不饱和脂肪酸（LCPUFA）、二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）的有效性系数较高，分别为 0.914（95%置信区间：0.665，0.997）和 0.889（95%置信区间：0.706，0.994）。在 Bland-Altman 图中，对于所有 PUFA，91-100%的观察值落在协议限之间。除 DPA 和 AA 外，初始 FFQ 和重复 FFQ 之间存在所有 PUFA 的显著相关性。
结论
PUFAFFQ 是评估终末期肾病患者多不饱和脂肪酸摄入量的有效工具。
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