Relationship between metabolic syndrome and metabolic syndrome score with -cell function by gender in non-diabetic Korean populations.

: The present study was conducted to assess the association of metabolic syndrome (MetS) and the MetS score (MSS) with -cell function by gender in Korean non-diabetic populations. : This study used the data from the 2015 Korean National Health and Nutrition Examination Survey including 4380 adults, aged 20 or older. : After adjusting for related variables (with exception of body mass index [BMI]), MetS (< 0.001) and MSS (< 0.001) were positively associated with homeostasis model assessment of -cell function (HOMA-), in both men and women. When further adjusting for BMI, MetS (= 0.002) and MSS (= 0.006) were positively associated with HOMA- in women, whereas the association of MetS (= 0.140) or MSS (= 0.697) and HOMA- was no longer significant in men. : MetS and MSS increases were positively associated with -cell function in non-diabetic Korean women, but not in non-diabetic Korean men.