Baumann Christian R
Department of Neurology, University Hospital Zurich, University of Zurich, Zürich, Switzerland.
Handb Exp Pharmacol. 2019;253:245-259. doi: 10.1007/164_2018_126.
Central disorders of hypersomnolence are characterized by daily periods of irrepressible need to sleep or daytime lapses into sleep, as defined in the current version of the International Criteria of Sleep Disorders. Thus, the unifying symptom is excessive daytime sleepiness which is not caused by any other sleep-wake disorder. Relevant disorders including narcolepsy type 1 and 2, idiopathic hypersomnia, Kleine-Levin syndrome, and insufficient sleep syndrome will be discussed. Other central disorders of hypersomnolence include hypersomnias due to medical or psychiatric disorders or because of medication or substance use.In sleep-related movement disorders, the cardinal symptom consists of simple, often stereotyped movements occurring during sleep. The most frequent disorder in this category of sleep-wake disorders is restless legs syndrome, which is often associated with period limb movements during sleep.
中枢性过度嗜睡障碍的特征是,按照当前版《国际睡眠障碍分类》的定义,患者每天都会出现无法抑制的睡眠需求期,或白天不由自主地入睡。因此,其共同症状是日间过度嗜睡,且并非由任何其他睡眠-觉醒障碍所致。将讨论相关障碍,包括1型和2型发作性睡病、特发性嗜睡症、克莱恩-莱文综合征和睡眠不足综合征。其他中枢性过度嗜睡障碍包括由医学或精神疾病、药物或物质使用引起的过度嗜睡。在与睡眠相关的运动障碍中,主要症状是睡眠期间出现的简单、常为刻板的运动。这类睡眠-觉醒障碍中最常见的疾病是不宁腿综合征,它常与睡眠期间的周期性肢体运动有关。