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“这是一份珍贵的礼物,不应浪费”:骨科手术中常规交叉配血是否必要?对9种不同手术的699例患者的回顾性研究。

"It's a precious gift, not to waste": is routine cross matching necessary in orthopedics surgery? Retrospective study of 699 patients in 9 different procedures.

作者信息

Hasan Obada, Khan Eraj Khurshid, Ali Moiz, Sheikh Sadaf, Fatima Anam, Rashid Haroon U

机构信息

Department of surgery, Section of Orthopaedics, The Aga Khan University Hospital (AKUH), National stadium road, P.O. Box 3500, Karachi, 74800, Pakistan.

The Aga Khan University Hospital (AKUH), Karachi, Pakistan.

出版信息

BMC Health Serv Res. 2018 Oct 20;18(1):804. doi: 10.1186/s12913-018-3613-9.

Abstract

BACKGROUND

Orthopedic surgeries are usually associated with excessive blood loss which leads surgeons to overestimate need for blood transfusions and over ordering of blood. The cross matched blood, when not used, leads to the wastage of blood bank resources in terms of time, money and manpower. The objective of this study was to investigate the compliance to previously proposed MSBOS and to provide updated recommendations for all orthopedic procedures.

METHODS

A retrospective analysis was conducted between 1st June 2015 and 31st May 2016. Patients admitted to the orthopedic surgery service for whom blood products were requested were included. Cross Match/Transfusion (CT) Ratio, Transfusion Index and Transfusion Probability were calculated. Values of < 2.5, > 0.5 and > 30% respectively, were taken as standards. Maximum Surgical Blood Ordering Schedule (MSBOS) was proposed based upon these calculations using Mead's criteria.

RESULTS

Six hundred and ninety-nine patients were sampled after implementing exclusion criteria. The overall CT ratio was 4.87, transfusion index was 0.55 and transfusion probability was 25%. A compliance rate of 24.6% was observed with the reference CT ratio of 2.5. Highest CT ratio was calculated for arthroscopic procedures while tumor resection had the lowest ratio. Age, procedure performed, ASA status and use of tourniquet were found to be significantly associated with CT ratio being greater or less than 2.5.

CONCLUSION

Results showed significant wastage of blood products and non-compliance with blood ordering guidelines. Hence there is need for large scale prospective studies to establish MSBOS and ensure its compliance.

摘要

背景

骨科手术通常伴随着大量失血,这导致外科医生高估输血需求并过度订购血液。交叉配血的血液若未使用,会在时间、金钱和人力方面造成血库资源的浪费。本研究的目的是调查对先前提出的最大外科手术用血计划(MSBOS)的依从性,并为所有骨科手术提供更新的建议。

方法

在2015年6月1日至2016年5月31日期间进行回顾性分析。纳入因请求血液制品而入住骨科手术科室的患者。计算交叉配血/输血(CT)比率、输血指数和输血概率。分别将<2.5、>0.5和>30%的值作为标准。基于这些计算并使用米德标准提出最大外科手术用血计划(MSBOS)。

结果

在实施排除标准后对699例患者进行了抽样。总体CT比率为4.87,输血指数为0.55,输血概率为25%。观察到参考CT比率为2.5时的依从率为24.6%。关节镜手术的CT比率最高,而肿瘤切除术的比率最低。发现年龄、所进行的手术、美国麻醉医师协会(ASA)分级状态和止血带的使用与CT比率大于或小于2.5显著相关。

结论

结果显示血液制品存在大量浪费且不符合用血订购指南。因此,需要进行大规模前瞻性研究以制定MSBOS并确保其依从性。

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