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单次麻醉下双侧一期全髋关节置换术仍安全吗?来自新西兰关节注册中心的一项16年队列研究。

Is single-anaesthetic bilateral primary total hip replacement still safe? A 16-year cohort study from the New Zealand Joint Registry.

作者信息

Wyatt Michael C, Hozack Joan W, Frampton Chris, Rothwell Alastair, Hooper Gary J

机构信息

Department of Orthopaedic Surgery and Musculoskeletal Medicine, Christchurch Public Hospital, Christchurch, New Zealand.

New Zealand Joint Registry, Christchurch Public Hospital, Christchurch, New Zealand.

出版信息

ANZ J Surg. 2018 Dec;88(12):1289-1293. doi: 10.1111/ans.14864. Epub 2018 Oct 22.

Abstract

BACKGROUND

The surgical management options for bilateral hip osteoarthritis comprise staged or single-anaesthetic bilateral total hip replacements (THRs). The key issue of contention in performing the latter remains safety. We compared unilateral, staged bilateral and single-anaesthetic bilateral THR with the hypothesis that there would be no difference between these three practices using mortality risk, functional outcome and revision rate as the primary outcome measures.

METHODS

We performed a retrospective cohort analysis of the New Zealand Joint Registry identifying all primary THRs performed between 1 January 1999 and 31 December 2015. We report this study in accordance with STROBE and RECORD guidelines. We identified all unilateral THRs, all single-anaesthetic bilateral THRs and all staged bilateral THRs and compared the mortality risk, all-cause revision risk with Kaplan-Meier survival analysis and reasons for revision and functional outcome using the Oxford 12 scores. Analysis was adjusted for age, gender, American Society of Anesthesiologists rating score and body mass index.

RESULTS

The mortality risk for single-anaesthetic bilateral THR within 3 months was 0.26% and for unilateral THR 0.75% (hazard ratio 0.35 (95% confidence interval (CI) 0.30-0.41, P < 0.001). The risk of revision in the single-anaesthetic bilateral THR group was 0.69/100 component years (95% CI 0.59-0.79/100 component years) versus 0.74/100 component years (95% CI 0.72-0.77/100 component years) in unilateral THR. Mean Oxford 12 scores at 6 months post-arthroplasty was 41.7 (95% CI 41.2-42.2) in the single-anaesthetic bilateral THR group. The best results in the staged bilateral THR group were obtained if the second procedure was delayed by at least 90 days from the first THR.

CONCLUSIONS

Single anaesthetic bilateral THR is at least as safe as unilateral THR or staged bilateral THR in appropriately selected cases. Experienced surgeons can expect predictable survival rates and functional scores.

摘要

背景

双侧髋关节骨关节炎的手术治疗方案包括分期或单次麻醉下的双侧全髋关节置换术(THR)。实施后者的关键争议点仍然是安全性。我们比较了单侧、分期双侧和单次麻醉双侧THR,假设以死亡率风险、功能结局和翻修率作为主要结局指标,这三种手术方式之间无差异。

方法

我们对新西兰关节注册中心进行了一项回顾性队列分析,确定了1999年1月1日至2015年12月31日期间进行的所有初次THR。我们按照STROBE和RECORD指南报告本研究。我们确定了所有单侧THR、所有单次麻醉双侧THR和所有分期双侧THR,并使用Kaplan-Meier生存分析比较死亡率风险、全因翻修风险,以及使用牛津12分评分比较翻修原因和功能结局。分析针对年龄、性别、美国麻醉医师协会评分和体重指数进行了调整。

结果

单次麻醉双侧THR在3个月内的死亡率风险为0.26%,单侧THR为0.75%(风险比0.35(95%置信区间(CI)0.30 - 0.41,P < 0.001)。单次麻醉双侧THR组的翻修风险为0.69/100部件年(95% CI 0.59 - 0.79/100部件年),而单侧THR为0.74/100部件年(95% CI 0.72 - 0.77/100部件年)。在关节置换术后6个月,单次麻醉双侧THR组的牛津12分平均评分为41.7(95% CI 41.2 - 42.2)。如果分期双侧THR组的第二次手术比第一次THR至少延迟90天,则可获得最佳结果。

结论

在适当选择的病例中,单次麻醉双侧THR至少与单侧THR或分期双侧THR一样安全。经验丰富的外科医生可以预期可预测的生存率和功能评分。

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