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慢性心力衰竭患者下腔静脉直径的预后意义

Prognostic Significance of Inferior Vena Caval Diameter in Patients with Chronic Heart Failure.

作者信息

Ghosh Sandip, Majumder Biswajit, Guharay Tapobrata, Tandel Viral, Gupta Sumana, Chatterjee Sharmistha

机构信息

Senior Resident.

Associate Professor.

出版信息

J Assoc Physicians India. 2018 Apr;66(4):40-2.

Abstract

BACKGROUND

Heart failure is a major public health problem with rising prevalence and accounts for a substantial number of OPD and emergency visits. Despite advances in pharmacotherapy and various devices being added to the armamentarium in managing heart failure the mortality continue to remain high. Therefore, we seek to find an easy bedside tool for risk stratification and prognostication of patients suffering from chronic heart failure for identifying patients with high risk and tailoring appropriate therapy for better outcome.

METHODS

Consecutive patients, clinically diagnosed as heart failure supported by objective evidence of cardiac dysfunction: either a LVEF 45% or LA dilatation, or both was studied to find out the etiologies, symptoms and signs, derangement of laboratory parameters and echocardiographic findings including IVC diameter and was followed up for six months at monthly intervals.

RESULTS

A prospective observational study was performed on 62 patients. Majority of heart failure occurred in the age group of 51 to 60 years. Acute coronary events, infections, arrhythmias were the commonest precipitating factors. An increase in LVIDD, LA diameter, LA volume index was significantly associated with increase in mortality (p=0.002, p=0.034, p=0.011 respectively. An increase in IVC diameter was found to be significantly associated with increased mortality (P=0.001).

CONCLUSION

In a country with limited resources like India, inferior vena caval diameter, as a surrogate marker of congestion, may prove to be a cost effective way in predicting and prognosticating patients with heart failure.

摘要

背景

心力衰竭是一个主要的公共卫生问题,其患病率不断上升,占门诊和急诊就诊人数的很大一部分。尽管药物治疗取得了进展,并且在心力衰竭管理的手段中增加了各种设备,但死亡率仍然居高不下。因此,我们试图找到一种简单的床边工具,用于对慢性心力衰竭患者进行风险分层和预后评估,以识别高危患者并制定适当的治疗方案以获得更好的结果。

方法

对连续的患者进行研究,这些患者临床诊断为心力衰竭,并伴有心脏功能障碍的客观证据:左心室射血分数(LVEF)≤45% 或左心房扩大,或两者兼有,以找出病因、症状和体征、实验室参数紊乱以及超声心动图结果,包括下腔静脉直径,并每月随访一次,持续六个月。

结果

对62例患者进行了一项前瞻性观察研究。大多数心力衰竭发生在51至60岁年龄组。急性冠状动脉事件、感染、心律失常是最常见的诱发因素。左心室舒张末期内径(LVIDD)、左心房直径、左心房容积指数的增加与死亡率增加显著相关(分别为p = 0.002、p = 0.034、p = 0.011)。发现下腔静脉直径增加与死亡率增加显著相关(P = 0.001)。

结论

在像印度这样资源有限的国家,下腔静脉直径作为充血的替代标志物,可能被证明是预测和评估心力衰竭患者的一种具有成本效益的方法。

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