Multisystem Involvement of Langerhans Cell Histiocytosis.

Langerhans cell histiocytosis presents with involvement of skin, bone and lungs. We discuss this case of breast LCH who developed pulmonary cystic lesions leading to bilateral pneumothoraces. PET scan showed involvement of thyroid and marrow involvement. A new nodule developed at ICD site after 9 months and was diagnosed as LCH nodule. This could be because of seeding of LCH cells at ICD site. We review LCH with involvement of multiple systems.