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引言:表观遗传学概念史概述

Introduction: sketches of a conceptual history of epigenesis.

作者信息

Nicoglou Antonine, Wolfe Charles T

机构信息

CRPMS & IJM, Sorbonne Paris Cité & IHPST Paris, Paris, France.

Ghent University, Ghent, Belgium.

出版信息

Hist Philos Life Sci. 2018 Oct 23;40(4):64. doi: 10.1007/s40656-018-0230-1.

Abstract

This is an introduction to a collection of articles on the conceptual history of epigenesis, from Aristotle to Harvey, Cavendish, Kant and Erasmus Darwin, moving into nineteenth-century biology with Wolff, Blumenbach and His, and onto the twentieth century and current issues, with Waddington and epigenetics. The purpose of the topical collection is to emphasize how epigenesis marks the point of intersection of a theory of biological development and a (philosophical) theory of active matter. We also wish to show that the concept of epigenesis existed prior to biological theorization and that it continues to permeate thinking about development in recent biological debates.

摘要

这是关于从亚里士多德到哈维、卡文迪什、康德和伊拉斯谟·达尔文的渐成论概念史的一系列文章的引言,接着进入19世纪生物学领域,探讨沃尔夫、布卢门巴赫和希斯的相关内容,再到20世纪及当前问题,涉及沃丁顿和表观遗传学。这个专题文集的目的是强调渐成论如何标志着生物发育理论与(哲学上的)活性物质理论的交汇点。我们还希望表明,渐成论的概念在生物学理论化之前就已存在,并且它在近期的生物学辩论中继续渗透到关于发育的思考中。

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