Gemici Ali, Şükür Yavuz Emre, Tülek Fırat, Taşkın Salih, Atabekoğlu Cem Somer
Ankara University Faculty of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey
J Turk Ger Gynecol Assoc. 2020 Mar 6;21(1):24-28. doi: 10.4274/jtgga.galenos.2018.2018.0087. Epub 2018 Oct 26.
To observe and compare the effect of postpartum tubal ligation (TL) procedures on ovarian reserve at women desiring TL as a contraceptive method at the end of pregnancy.
Eighty-one women were included in the prospective study. TL was performed at the time of cesarean delivery (CD) (n=49) and as an interval procedure by laparoscopy (LS) in the postpartum period (n=32). Anti-müllerian hormone (AMH) was used to determine ovarian reserve. Blood samples were taken twice from each subject; the first sample was taken before delivery from all subjects and the second sample was taken 4 months after sterilization. AMH level differences were compared in each group and between groups.
The preoperative AMH values of CD and LS groups were similar 2.30 (maximum: 5.20, minimum: 0.42) ng/mL and 1.80 (maximum: 3.50, minimum: 0.40) ng/mL, respectively (p=0.262). The postoperative AMH values of the CD and LS groups were 1.30 (maximum: 2.60, minimum: 0.30) ng/mL and 0.90 (maximum: 2.50, minimum: 0.20) ng/mL, respectively (p=0.284). When the preoperative and postoperative values of each group were compared the change was statistically significant for both groups p<0.001. The decrease in mean AMH values in the CD and LS groups were 37.83% and 44.15%, respectively. The percentage changes of AMH values were not statistically significant (p=0.286).
TL at the time of CD and interval sterilization with LS have similar effects on ovarian reserve.
观察并比较产后输卵管结扎(TL)手术对妊娠末期希望采用TL作为避孕方法的女性卵巢储备功能的影响。
81名女性纳入前瞻性研究。剖宫产(CD)时进行TL(n = 49),产后期间通过腹腔镜检查(LS)作为间隔手术进行TL(n = 32)。使用抗苗勒管激素(AMH)来确定卵巢储备功能。从每个受试者采集两次血样;所有受试者在分娩前采集第一份样本,绝育后4个月采集第二份样本。比较每组以及组间的AMH水平差异。
CD组和LS组术前AMH值相似,分别为2.30(最大值:5.20,最小值:0.42)ng/mL和1.80(最大值:3.50,最小值:0.40)ng/mL(p = 0.262)。CD组和LS组术后AMH值分别为1.30(最大值:2.60,最小值:0.30)ng/mL和0.90(最大值:2.50,最小值:0.20)ng/mL(p = 0.284)。比较每组术前和术后的值,两组的变化均具有统计学意义(p<0.001)。CD组和LS组平均AMH值的下降分别为37.83%和44.15%。AMH值的百分比变化无统计学意义(p = 0.286)。
剖宫产时进行TL和通过LS进行间隔绝育对卵巢储备功能的影响相似。