在介入放射科套房中进行经皮内镜下经胃空肠造口术（PEG-J）置管用于左旋多巴-卡比多巴空肠内凝胶治疗：长期随访
Percutaneous Endoscopic Transgastric Jejunostomy (PEG-J) Tube Placement for Levodopa-Carbidopa Intrajejunal Gel Therapy in the Interventional Radiology Suite: A Long-term Follow-up.
作者信息
Saddi Maria Valeria, Sarchioto Marianna, Serra Giulia, Murgia Daniela, Ricchi Valeria, Melis Marta, Arca Roberta, Carreras Pierpaolo, Sitzia Loredana, Zedda Sandro, Dui Giovanni, Rossi Rosario, Ticca Anna, Melis Maurizio, Cossu Giovanni
机构信息
Neurology Department and Stroke Unit S. Francesco Hospital Nuoro Italy.
Neurology Department and Stroke Unit Azienda Ospedaliera Brotzu "G. Brotzu" Hospital Cagliari Sardinia Italy.
出版信息
Mov Disord Clin Pract. 2018 Jan 3;5(2):191-194. doi: 10.1002/mdc3.12569. eCollection 2018 Mar-Apr.
BACKGROUND
Percutaneous endoscopic gastrojejunostomy (PEG) and radiologically inserted gastrojejunostomy (RIG) are both safe and effective techniques for gastrojejunal tube placement. The authors compared these 2 procedures in patients with advanced Parkinson's disease (PD) who required the continuous intrajejunal delivery of a levodopa/carbidopa gel suspension (LCIG).
METHODS
Outcomes were retrospectively collated from 30 PEG and 12 RIG procedures performed at 2 centers in patients with advanced PD for the delivery of LCIG.
RESULTS
Baseline clinical characteristics, incidence of early severe adverse events, late major complications, dropout, and the mean time-lapse of tube replacements were comparable in the PEG and RIG groups.
CONCLUSION
The current results suggest that, in patients with PD, the RIG technique is as safe and effective as the endoscopic procedure, and it can be considered a valid option for patients who require LCIG when the endoscopic procedure is not available or unfeasible.
背景
经皮内镜下胃空肠造口术（PEG）和放射介入下胃空肠造口术（RIG）都是安全有效的胃空肠置管技术。作者比较了这两种手术在需要持续空肠内输注左旋多巴/卡比多巴凝胶悬浮液（LCIG）的晚期帕金森病（PD）患者中的应用情况。
方法
回顾性整理了在2个中心为晚期PD患者进行的30例PEG手术和12例RIG手术的结果，这些手术均用于LCIG的输注。
结果
PEG组和RIG组在基线临床特征、早期严重不良事件发生率、晚期主要并发症、退出率以及平均更换导管时间间隔方面具有可比性。
结论
目前的结果表明，在PD患者中，RIG技术与内镜手术一样安全有效，对于在内镜手术不可用或不可行时需要LCIG的患者，它可被视为一种有效的选择。
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