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孕妇意识模糊状态:一例妊娠期间 NMDA 受体脑炎。

Confusional state in a pregnant woman: A case of NMDA receptor encephalitis during pregnancy.

机构信息

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Neuroimmunol. 2018 Dec 15;325:29-31. doi: 10.1016/j.jneuroim.2018.10.008. Epub 2018 Oct 19.

Abstract

We report the case of a pregnant female presenting with behavioral change and hallucinations followed by focal seizures with impaired awareness. EEG revealed generalized slowing interspersed with extreme delta-brush pattern and MRI brain was normal. Both Serum and CSF anti-N-methyl-d-aspartate receptor (NMDAR) antibodies were positive. Patient had a prolonged hospital stay with full recovery and delivered a healthy baby, highlighting the significance of early diagnosis and management in this disorder.

摘要

我们报告了一例表现为行为改变和幻觉,继而出现意识障碍局灶性癫痫发作的孕妇病例。脑电图显示弥漫性减慢,夹杂着极度德尔塔刷样波,脑 MRI 正常。血清和脑脊液抗 N-甲基-D-天冬氨酸受体(NMDAR)抗体均为阳性。患者住院时间延长,完全康复并生下了健康的婴儿,这凸显了早期诊断和治疗在这种疾病中的重要性。

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