Centro Hospitalar de Vila Nova de Gaia e Espinho, Gastrenterology Department, Vila Nova de Gaia, Portugal.
Centro Hospitalar de Vila Nova de Gaia e Espinho, Gastrenterology Department, Vila Nova de Gaia, Portugal.
Dig Liver Dis. 2019 Jan;51(1):75-78. doi: 10.1016/j.dld.2018.09.029. Epub 2018 Oct 6.
The guidelines by the American Society for Gastrointestinal Endoscopy (ASGE) suggest that in patients with gallbladder in situ, endoscopic retrograde cholangiopancreatography (ERCP) should be performed in the presence of high-risk criteria for choledocholithiasis, after biochemical tests and abdominal ultrasound. There are no specific recommendations for cholecystectomized patients. The aim of this study was to evaluate the applicability of ASGE criteria for ERCP in cholecystectomized patients with suspected choledocholithiasis.
We conducted a retrospective study that included patients with high-risk ASGE criteria for choledocholithiasis who underwent ERCP from 2013-2016.
We included 327 patients in our analysis - 258 with gallbladder in situ (79%) and 69 with cholecystectomy (21%). We showed that the ASGE criteria true positive rate was similar between patients with and without cholecystectomy - the prevalence of choledocholithiasis on ERCP was 71% in cholecystectomized and 70% in non-cholecystectomized. In addition, both the presence and the diameter of the CBD stone were predictors of positive ERCP in both groups. In contrast, the diameter of the CBD was predictor of positive ERCP only in non-cholecystectomized patients.
Although dilatation of the CBD was not a predictive factor for choledocholithiasis in cholecystectomized patients, the ASGE criteria true positive rate was similar to that of non-cholecystectomized patients.
美国胃肠内镜学会(ASGE)指南建议,对于存在胆总管结石高危因素的胆囊原位患者,在生化检查和腹部超声检查后,应行内镜逆行胰胆管造影(ERCP)。对于已行胆囊切除术的患者,尚无具体推荐意见。本研究旨在评估 ASGE 标准对疑似胆总管结石的已行胆囊切除术患者行 ERCP 的适用性。
我们进行了一项回顾性研究,纳入了 2013-2016 年间因存在 ASGE 胆总管结石高危因素而行 ERCP 的患者。
我们共纳入 327 例患者,其中 258 例(79%)为胆囊原位,69 例(21%)为胆囊切除。我们发现,胆囊切除与未切除患者的 ASGE 标准真阳性率相似——ERCP 胆总管结石的检出率在胆囊切除组为 71%,在未切除组为 70%。此外,CBD 结石的存在和直径均为两组患者 ERCP 阳性的预测因素。相比之下,CBD 直径仅为未切除患者 ERCP 阳性的预测因素。
尽管在胆囊切除患者中,CBD 扩张不是胆总管结石的预测因素,但 ASGE 标准的真阳性率与未切除患者相似。