Ibrahim Fady, Dunn Jonathan, Rundback John, Pellerito John, Galmer Andrew
Zucker School of Medicine at Hofstra Northwell, Northshore University Hospital, 300 Community Drive, Manhasset, NY, 11030, USA.
Holy Name Medical Center, 718 Teaneck Road, Teaneck, NJ, 07666, USA.
Curr Treat Options Cardiovasc Med. 2018 Oct 26;20(12):97. doi: 10.1007/s11936-018-0696-x.
Visceral artery aneurysms (VAAs) are a rare, but serious clinical entity as rupture confers a high rate of mortality. Data regarding the prevalence, treatment, and prognosis of VAAs is largely from case series, as true randomized trials are lacking. The incidence of VAAs has risen over the decades with advances in imaging technology, availability, and utilization. Even in the presence of symptoms, the prompt diagnosis of VAAs may be challenging as symptoms are often nonspecific and varied. Although there are no definitive treatment guidelines, asymptomatic VAAs require treatment in the following scenarios: when the aneurysm diameter is greater than 2 cm, when identified during pregnancy, when multiple aneurysms are present, and in the case of hepatic transplant. Similar to therapeutic trends in other vascular beds, advances in endovascular devices and techniques have driven an "endovascular first" approach for the treatment of VAAs. However, although the success rates of endovascular repair are impressive, surgical intervention is still necessary in treating centers. This paper reviews the pathophysiology, clinical features, anatomic characteristics, and management strategies required for the effective diagnosis and treatment of VAAs.
内脏动脉瘤(VAA)是一种罕见但严重的临床病症,因为破裂会导致高死亡率。关于VAA的患病率、治疗和预后的数据主要来自病例系列,因为缺乏真正的随机试验。随着成像技术、可及性和利用率的进步,几十年来VAA的发病率有所上升。即使出现症状,VAA的及时诊断也可能具有挑战性,因为症状往往是非特异性且多样的。尽管没有明确的治疗指南,但无症状VAA在以下情况下需要治疗:动脉瘤直径大于2厘米、在怀孕期间发现、存在多个动脉瘤以及在肝移植的情况下。与其他血管床的治疗趋势类似,血管内装置和技术的进步推动了“血管内优先”的VAA治疗方法。然而,尽管血管内修复的成功率令人印象深刻,但在治疗中心手术干预仍然是必要的。本文综述了有效诊断和治疗VAA所需的病理生理学、临床特征、解剖学特征和管理策略。