e2H, West Corporation, Westlake Village, CA, USA.
Centre for Health Systems and Safety Research, Macquarie University, North Ryde, New South Wales, Australia.
Occup Med (Lond). 2018 Dec 26;68(9):610-616. doi: 10.1093/occmed/kqy138.
Workplace health screening offers a unique opportunity to assess individuals for type 2 diabetes mellitus.
To evaluate the association between workplace diabetes screening, subsequent diagnosis and changes in fasting plasma glucose (FPG), glycated haemoglobin (HbA1c) and body mass index (BMI) among individuals who screened positive for diabetes.
Employees without a prior diagnosis of diabetes participated in workplace health screening by 45 employers throughout the USA. Individuals screened positive for diabetes based on standard criteria (≥126 mg/dL FPG or ≥6.5% [48 mmol/mol] HbA1c). Diabetes diagnoses were identified after screening using claims-based ICD9-CM diagnosis codes. Discrete-time survival analysis estimated the monthly rate of new diabetes cases after screening, relative to the time period before screening. Paired t-tests evaluated 1-year changes in blood glucose measures and BMI among individuals with positive screenings.
Of 22790 participating individuals, 900 (4%) screened positive for diabetes. A significantly greater rate of new diabetes diagnoses was observed during the first month after screening, compared to the 3-month period before screening (odds ratio [OR] 2.65, 95% confidence intervals [CIs] 2.02-3.47). Among 538 individuals with diabetes who returned for workplace screening 1 year later, significant improvements were observed in BMI (mean ± SD = -0.63 ± 2.56 kg/m2, P < 0.001) and FPG levels (mean ± SD = -9.3 ± 66.5 mg/dL, P < 0.01).
Workplace screening was associated with a reduction in the number of undiagnosed employees with diabetes and significant improvement in FPG and BMI at 1-year follow-up.
工作场所健康筛查为评估个体 2 型糖尿病提供了独特的机会。
评估工作场所糖尿病筛查与随后诊断之间的关联,以及在筛查出糖尿病阳性的个体中,空腹血浆葡萄糖(FPG)、糖化血红蛋白(HbA1c)和体重指数(BMI)的变化。
来自美国各地 45 家雇主的无糖尿病既往史的员工参加了工作场所健康筛查。根据标准标准(FPG≥126mg/dL 或 HbA1c≥6.5%[48mmol/mol])筛查出糖尿病阳性的个体。使用基于索赔的 ICD9-CM 诊断代码在筛查后确定糖尿病诊断。离散时间生存分析估计了筛查后与筛查前时间段相比,新的糖尿病病例的每月发生率。配对 t 检验评估了筛查阳性个体 1 年内血糖指标和 BMI 的变化。
在 22790 名参与的个体中,有 900 名(4%)筛查出糖尿病阳性。与筛查前 3 个月相比,在筛查后第一个月观察到新的糖尿病诊断的发生率显著更高(比值比[OR]2.65,95%置信区间[CI]2.02-3.47)。在 538 名 1 年后返回工作场所筛查的糖尿病患者中,观察到 BMI(平均值±标准差=-0.63±2.56kg/m2,P<0.001)和 FPG 水平(平均值±标准差=-9.3±66.5mg/dL,P<0.01)显著改善。
工作场所筛查与未确诊的糖尿病患者数量减少以及 FPG 和 BMI 在 1 年随访时的显著改善相关。