Aj Ashwal, Razak Uk Abdul, R Padmakumar, Pai Umesh, M Sudhakar
Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India, India.
Indian Heart J. 2018 Sep-Oct;70(5):690-698. doi: 10.1016/j.ihj.2018.01.013. Epub 2018 Jan 10.
Central venous stenosis is an important hindrance to long-term maintenance of arteriovenous access in the upper extremities in dialysis patients.
The present study was done to determine feasibility and clinical success of endovascular approach for the treatment of symptomatic central venous stenosis associated with significant ipsilateral limb edema in dialysis patients with vascular access in the upper limb.
A database of hemodialysis patients who underwent endovascular treatment for central venous stenosis from January 2014 to January 2017 at our institute was retrospectively reviewed. Follow-up was variable.
The study included ten patients (6 men and 4 women) with a mean age of 45.2 years, who underwent thirteen interventions during a period of 3 years. The technical success rate for endovascular treatment was 100%. One patient underwent primary PTA (percutaneous transluminal angioplasty). Seven patients underwent primary PTA and stenting. Three patients underwent secondary PTA. One among these patients underwent secondary PTA twice along with fistuloplasty. One patient underwent secondary PTA with stenting. No immediate complications were encountered during the procedure. Our study shows a primary patency rate of 67% and 33% at 6 months and 12 months for PTA with stenting. Our study also shows secondary or assisted primary patency of 75% at 6 months of follow-up.
Endovascular therapy (PTA) with or without stenting for central venous stenosis is safe, with low rates of technical failure. Multiple additional interventions are the rule and long-term patency rate is not very good.
中心静脉狭窄是透析患者上肢动静脉通路长期维持的重要障碍。
本研究旨在确定血管内介入治疗伴有明显同侧肢体水肿的透析患者上肢血管通路相关症状性中心静脉狭窄的可行性和临床成功率。
回顾性分析2014年1月至2017年1月在我院接受中心静脉狭窄血管内治疗的血液透析患者数据库。随访情况不一。
该研究纳入10例患者(6例男性和4例女性),平均年龄45.2岁,在3年期间接受了13次干预。血管内治疗的技术成功率为100%。1例患者接受了初次经皮腔内血管成形术(PTA)。7例患者接受了初次PTA和支架置入术。3例患者接受了二次PTA。其中1例患者在接受二次PTA的同时进行了两次内瘘成形术。1例患者接受了二次PTA并置入支架。术中未出现即刻并发症。我们的研究显示,PTA联合支架置入术在6个月和12个月时的初次通畅率分别为67%和33%。我们的研究还显示,随访6个月时二次或辅助初次通畅率为75%。
血管内治疗(PTA)联合或不联合支架置入治疗中心静脉狭窄是安全的,技术失败率低。多次额外干预是常态,长期通畅率不太理想。