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恶性骨肿瘤的外科治疗

Surgical management of malignant bone tumours.

作者信息

Miller T R

出版信息

Can J Surg. 1977 Nov;20(6):513-7.

PMID:303930
Abstract

The evolution of treatment for osteogenic sarcoma at the Memorial Sloan-Kettering Cancer Center is reviewed. The possible control of micrometastases by chemotherapy and the excision of macrometastases at single or multiple thoracotomies by the thoracic surgeon have added greatly to the salvage rate of this tumour. Intensive chemotherapy has made possible en bloc resection of bones involved by tumour, with preservation of the limb. Despite advances, however, amputation or en bloc resection is still necessary to control the primary tumour.

摘要

本文回顾了纪念斯隆凯特琳癌症中心骨肉瘤治疗方法的演变。化疗对微转移的潜在控制以及胸外科医生通过单次或多次开胸手术切除大转移灶,极大地提高了这种肿瘤的挽救率。强化化疗使得整块切除受肿瘤累及的骨骼并保留肢体成为可能。然而,尽管取得了进展,但截肢或整块切除对于控制原发性肿瘤仍然是必要的。

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