Papavasiliou Athanasios V, Triantafyllopoulos Ioannis, Paxinos Odysseas, Tsoukas Dimitrios, Kostantoulakis Charalambos
Interbalkan Medical Center of Thessaloniki, 10 Asclepiou Str., Pylaia, Thessaloniki, Greece.
National and Kapodestrian University of Athens, KAT Hospital, 2 Nikis Str., Kifissia, Greece.
J Hip Preserv Surg. 2018 Jun 14;5(3):202-208. doi: 10.1093/jhps/hny021. eCollection 2018 Aug.
The exact pathophysiology of osteonecrosis of the femoral head (ONFH) is still unknown. There is evidence to suggest that in ON there is decreased population and altered function of the mesenchymal stem cells (MSCs) of the femoral head. This could influence both the actual occurrence of ON itself and the repair process that follows. Hence, in such an environment it only is rational to consider the use of cell-based treatments to potentially regenerate lost or damaged bone. The aim of this review is to provide an up-to-date, evidence-based information in the use of cell therapies in the treatment of nontraumatic ONFH and the use of hip arthroscopy in the field.
股骨头坏死（ONFH）的确切病理生理学仍不清楚。有证据表明，在骨坏死中，股骨头间充质干细胞（MSCs）数量减少且功能改变。这可能会影响骨坏死本身的实际发生情况以及随后的修复过程。因此，在这样的环境下，考虑使用基于细胞的治疗方法来潜在地再生丢失或受损的骨骼是合理的。本综述的目的是提供关于细胞疗法在非创伤性股骨头坏死治疗中的最新、循证信息，以及该领域中髋关节镜检查的应用情况。
Zotero 插件