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东亚长期护理机构认知障碍老年居民痴呆行为和心理症状的患病率:一项横断面研究。

Prevalence of behavioural and psychological symptoms of dementia in cognitively impaired elderly residents of long-term care facilities in East Asia: a cross-sectional study.

机构信息

Department of Health Sciences, Graduate School of Medicine, Osaka University, Osaka, Japan.

Department of Nursing, School of Nursing and Rehabilitation, Konan Women's University, Kobe, Japan.

出版信息

Psychogeriatrics. 2019 Mar;19(2):171-180. doi: 10.1111/psyg.12380. Epub 2018 Nov 4.

Abstract

OBJECTIVE

The aim of this study was to compare the prevalence of behavioural and psychological symptoms of dementia (BPSD) in cognitively impaired elderly residents of long-term care facilities in East Asia and to explore the factors associated with these patterns.

METHODS

This was a cross-sectional survey of BPSD in cognitively impaired elderly residents of long-term care facilities in Japan, South Korea, China, Taiwan, and Thailand. The Mini-Mental State Examination, Clinical Dementia Rating (CDR), and Neuropsychiatric Inventory, Nursing Home version (NPI-NH), were used to assess cognitive status, dementia severity, and BPSD, respectively. NPI-NH subscale severity scores were multiplied by frequency scores to obtain the subscale scores and aggregated into two groups based on score (clinically insignificant = 1- 3; clinically significant ≥4).

RESULTS

Data from 662 people were analyzed. Median age, median Mini-Mental State Examination scores, and median CDR scores differed significantly among the seven study sites. The prevalence of BPSD varied from 64% in Taiwan to 100% in dementia care units in Japan, and the median total NPI-NH scores ranged from 2 in Taiwan to 14 in dementia care units in Japan. After stratification of the sample by dementia severity and clinical significance of NPI-NH scores, differences in the prevalence of clinically significant BPSD were mostly observed among facilities dedicated to dementia patients in the CDR 1 group. In the CDR 3 group, the prevalence of some clinically significant BPSD, such as apathy, was high even among study sites with low median total NPI-NH scores.

CONCLUSIONS

Our findings may suggest referral and selection biases in the study sites. Future prospective studies are needed to address the impact of environmental and care factors on the occurrence of BPSD in Asian countries.

摘要

目的

本研究旨在比较东亚认知障碍长期护理机构老年居民的行为和心理症状(BPSD)的患病率,并探讨与这些模式相关的因素。

方法

这是一项针对日本、韩国、中国、中国台湾和泰国认知障碍长期护理机构老年居民的 BPSD 的横断面调查。使用简易精神状态检查、临床痴呆评定量表(CDR)和神经精神问卷,长期护理机构版(NPI-NH)分别评估认知状态、痴呆严重程度和 BPSD。NPI-NH 子量表严重程度评分乘以频率评分,以获得子量表评分,并根据评分(无临床意义=1-3;有临床意义≥4)将其分为两组。

结果

共分析了 662 人的数据。七个研究地点的中位年龄、中位简易精神状态检查评分和中位 CDR 评分存在显著差异。BPSD 的患病率从中国台湾的 64%到日本痴呆护理单元的 100%不等,中位 NPI-NH 总分从中国台湾的 2 到日本痴呆护理单元的 14 不等。对样本按痴呆严重程度和 NPI-NH 评分的临床意义分层后,在 CDR1 组中,痴呆患者专用设施中观察到临床显著 BPSD 的患病率差异最大。在 CDR3 组中,即使在总 NPI-NH 评分中位数较低的研究地点,某些临床显著 BPSD(如冷漠)的患病率也很高。

结论

我们的发现可能表明研究地点存在转诊和选择偏倚。未来需要进行前瞻性研究,以解决环境和护理因素对亚洲国家 BPSD 发生的影响。

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