Manwani Bharti, Rath Subhendu, Lee Nora S, Staff Ilene, Stretz Christoph, Modak Janhavi, Finelli Pasquale F
Department of Neurology and Neuroscience, UT health Science Center of Houston, Houston, Texas.
Department of Neurology, UConn Health and Hartford Hospital, Farmington/Hartford, Connecticut.
J Stroke Cerebrovasc Dis. 2019 Feb;28(2):425-429. doi: 10.1016/j.jstrokecerebrovasdis.2018.10.015. Epub 2018 Nov 3.
Imaging modalities are important part of stroke evaluation. Noncontrast head computed tomography (CT) is the initial imaging modality in acute stroke and although important to rule out acute hemorrhage and making a decision on thrombolytic treatment, ischemic changes may not be visible on CT for up to 24 hours. Magnetic resonance imaging (MRI) brain is an invaluable tool to confirm an ischemic stroke and facilitates stroke evaluation. Objective of this study was to investigate the correlation between time to MRI and length of hospital stay.
A total of 432 patients admitted to Hartford Hospital (Comprehensive Stroke Center) with a focal neurological deficit in the year 2014 and got a CT head and MRI brain were enrolled in the study. Data collection was done via stroke database and retrospective chart review. Patients with any hemorrhage or age <18 years were excluded from the study. Patients were categorized as having had an early (within 12 hours) or a late (more than 12 hours) MRI. We used chi-square and Wilcoxon ranked sum test to compare time from arrival to MRI and length of stay in the hospital.
There was a statistically significant difference in hospital length of stay between patients who obtained MRI within 12 hours, as compared with patients who had MRI greater than 12 hours after admission, early MRI group 3 days (1.8, 4.9) versus 4 days (2.6, 7.0), P < .001.
Our study suggests that brain MRI performed within 12 hours of admission facilitates stroke evaluation and decreases hospital length of stay. It provides evidence for cost effectiveness of MRI in ischemic stroke.
成像方式是卒中评估的重要组成部分。非增强头部计算机断层扫描(CT)是急性卒中的初始成像方式,虽然对于排除急性出血和决定溶栓治疗很重要,但缺血性改变在CT上可能长达24小时都不可见。脑部磁共振成像(MRI)是确认缺血性卒中并促进卒中评估的宝贵工具。本研究的目的是调查进行MRI的时间与住院时间之间的相关性。
2014年共有432名入住哈特福德医院(综合卒中中心)且有局灶性神经功能缺损并接受了头部CT和脑部MRI检查的患者纳入本研究。数据收集通过卒中数据库和回顾性病历审查完成。任何有出血或年龄<18岁的患者被排除在研究之外。患者被分类为早期(12小时内)或晚期(超过12小时)进行MRI检查。我们使用卡方检验和Wilcoxon秩和检验来比较从入院到进行MRI的时间和住院时间。
与入院后超过12小时进行MRI检查的患者相比,在12小时内进行MRI检查的患者住院时间存在统计学上的显著差异,早期MRI组为3天(1.8,4.9),而晚期为4天(2.6,7.0),P <.001。
我们的研究表明,入院后12小时内进行脑部MRI检查有助于卒中评估并缩短住院时间。它为MRI在缺血性卒中中的成本效益提供了证据。