Canbolat Nur, Buget Mehmet Ilke, Sivrikoz Nukhet, Altun Demet, Kucukay Suleyman
Istanbul University, Istanbul Medical Faculty, Department of Anesthesiology, Istanbul, Turquia.
Istanbul University, Istanbul Medical Faculty, Department of Anesthesiology, Istanbul, Turquia.
Braz J Anesthesiol. 2019 Jan-Feb;69(1):42-47. doi: 10.1016/j.bjan.2018.07.004. Epub 2018 Nov 3.
Neutrophil to lymphocyte ratio is a simple, cost-effective and easily applicable inflammation indicator that is being used frequently in mortality, morbidity and prognosis studies in the recent years. We evaluated the relationship between neutrophil to lymphocyte ratio and postoperative pain in patients undergoing total hip arthroplasty and total knee arthroplasty.
We included 101 patients who preferred spinal anesthesia and intravenous patient-controlled analgesia in accordance and divided them into two groups, total hip arthroplasty and total knee arthroplasty. We recorded demographic information, duration of operation, length of hospital stay, analgesics consumption, neutrophil to lymphocyte ratio results and postoperative pain using Visual Analog Scale.
The morphine consumption of the patients was as follows in group total hip arthroplasty and total knee arthroplasty: at the 4th hour: 7.38 mg, 7.80 mg; 8th hour: 12.19 mg, 13.29 mg; 12th hour: 16.94 mg, 19.18 mg; 24th hour: 25.97 mg, 27.98 mg; 48th hour: 36.38 mg, 39.59 mg. The Visual Analog Scale scores of the patients was as follows in group total hip arthroplasty and total knee arthroplasty: at the 4th hour: 4.10, 4.51; 8th hour: 3.02, 3.43; 12th hour: 2.29, 2.55; 24th hour: 1.90, 1.87; 48th hour: 1.08, 1.13. In group total hip arthroplasty, we found a statistically significant association between postoperative neutrophil to lymphocyte ratio and the Visual Analog Scale values on the 48th hour in a positive direction ( = 0.311; = 0.031; < 0.05).
Neutrophil to lymphocyte ratio can be accepted as a relatively objective method for the diagnosis of postoperative pain.
中性粒细胞与淋巴细胞比值是一种简单、经济且易于应用的炎症指标，近年来在死亡率、发病率和预后研究中被频繁使用。我们评估了全髋关节置换术和全膝关节置换术患者中性粒细胞与淋巴细胞比值与术后疼痛之间的关系。
我们纳入了101例选择脊髓麻醉和静脉自控镇痛的患者，并将他们分为两组，即全髋关节置换术组和全膝关节置换术组。我们记录了人口统计学信息、手术时长、住院时间、镇痛药用量、中性粒细胞与淋巴细胞比值结果以及使用视觉模拟评分法评估的术后疼痛情况。
全髋关节置换术组和全膝关节置换术组患者的吗啡用量如下：第4小时：7.38毫克，7.80毫克；第8小时：12.19毫克，13.29毫克；第12小时：16.94毫克，19.18毫克；第24小时：25.97毫克，27.98毫克；第48小时：36.38毫克，39.59毫克。全髋关节置换术组和全膝关节置换术组患者的视觉模拟评分如下：第4小时：4.10，4.51；第8小时：3.02，3.43；第12小时：2.29，2.55；第24小时：1.90，1.87；第48小时：1.08，1.13。在全髋关节置换术组中，我们发现术后中性粒细胞与淋巴细胞比值与第48小时的视觉模拟评分值之间存在统计学显著的正相关关系（r = 0.311；P = 0.031；P < 0.05）。
中性粒细胞与淋巴细胞比值可被视为诊断术后疼痛的一种相对客观的方法。
