Samura Makoto, Morikage Noriyasu, Mizoguchi Takahiro, Takeuchi Yuriko, Nagase Takashi, Harada Takasuke, Suehiro Kotaro, Hamano Kimikazu
Division of Vascular Surgery, Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
Ann Vasc Dis. 2018 Sep 25;11(3):259-264. doi: 10.3400/avd.ra.18-00064.
Type II endoleak is a common complication that develops after endovascular aneurysm repair. Patients with type II endoleak, which has persisted for 6 months, have a significantly higher rate of aneurysmal sac enlargement, reintervention, and rupture. To date, several studies have examined the effectiveness of preoperative embolization of branch vessels for the prevention of type II endoleak. Particularly, the embolization of the large inferior mesenteric artery (IMA) seems to be a precise, safe, and effective method. IMA is a significant risk factor for type II endoleak. However, there is currently no strong evidence to prove which patients would benefit from preventive IMA embolization. In addition, considering the incidence of type II endoleak and the adverse event rate, routine embolization seems to be unreliable and time-consuming. Moreover, previous reports of preoperative IMA embolization were retrospective. Thus, prospective and randomized studies are necessary so that the usefulness of IMA embolization can be proved and the potential benefits can be assessed. To establish preventive IMA embolization as one of the effective therapeutic strategies to prevent type II endoleak and to maximize its therapeutic effect, we should provide a wide range of therapeutic strategies to suit the state of the patient.
II型内漏是血管内动脉瘤修复术后常见的并发症。持续6个月的II型内漏患者,其动脉瘤囊扩大、再次干预和破裂的发生率显著更高。迄今为止,已有多项研究探讨了术前对分支血管进行栓塞以预防II型内漏的有效性。特别是,对肠系膜下动脉(IMA)主干进行栓塞似乎是一种精确、安全且有效的方法。IMA是II型内漏的一个重要危险因素。然而,目前尚无有力证据证明哪些患者会从预防性IMA栓塞中获益。此外,考虑到II型内漏的发生率和不良事件发生率,常规栓塞似乎并不可靠且耗时。而且,既往关于术前IMA栓塞的报道均为回顾性研究。因此,有必要进行前瞻性随机研究,以证明IMA栓塞的有效性并评估其潜在益处。为了将预防性IMA栓塞确立为预防II型内漏的有效治疗策略之一,并使其治疗效果最大化,我们应提供广泛的治疗策略以适应患者的病情。