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骨科医师的血栓弹力描记术。

Thromboelastography for the Orthopaedic Surgeon.

机构信息

From the Department of Orthopaedic Surgery and Rehabilitation, University of Texas Medical Branch Galveston, Galveston, TX (Dr. Hagedorn, Dr. Paris, and Dr. Lindsey), and the Division of Acute Care Surgery LAC + USC Medical Center, University of Southern California, Los Angeles, CA (Dr. Bardes).

出版信息

J Am Acad Orthop Surg. 2019 Jul 15;27(14):503-508. doi: 10.5435/JAAOS-D-17-00603.

Abstract

Evaluation of coagulation is vital in the care of the orthopaedic patients, particularly in the subspecialties of trauma, spine, arthroplasty, and revision surgery resulting from blood loss and coagulopathies. Although conventional tests (prothrombin time/international normalized ratio, activated partial thromboplastin time, platelet count, and fibrinogen) are most commonly used, others like thromboelastography (TEG) are also available to the orthopaedic surgeons. TEG is a blood test developed in the 1950s, which provides a snapshot of a patient's coagulation profile by evaluating clot formation and lysis. Recently, TEG has been used to assess traumatic coagulopathy. The coagulation parameters measured by the TEG are reaction time (R-time), time to reach a certain clot strength (K-value), speed of fibrin build up (α-angle), maximum clot amplitude, and percentage decrease of clot in 30 minutes (LY30). Using these values, traumatologists have developed a better, faster, and more accurate overview of a patient's resuscitation and more successfully direct blood product use. However, many orthopaedic surgeons-despite performing surgical procedures that risk notable blood loss and postoperative clotting complications-are unaware of the existence of the TEG blood test and the critical information it provides. Increasing awareness of the TEG among orthopaedic surgeons could have a notable effect on numerous aspects of musculoskeletal care.

摘要

在骨科患者的护理中,评估凝血至关重要,特别是在创伤、脊柱、关节置换和因失血和凝血障碍而进行的翻修手术等亚专科中。虽然常规测试(凝血酶原时间/国际标准化比值、活化部分凝血活酶时间、血小板计数和纤维蛋白原)最常用于评估凝血功能,但骨科医生也可以使用血栓弹力图(TEG)等其他测试。TEG 是一种 20 世纪 50 年代开发的血液测试,通过评估血栓形成和溶解,提供患者凝血概况的快照。最近,TEG 已用于评估创伤性凝血障碍。TEG 测量的凝血参数包括反应时间(R 时间)、达到一定血栓强度的时间(K 值)、纤维蛋白形成速度(α 角)、最大血栓幅度和 30 分钟内血栓减少的百分比(LY30)。使用这些值,创伤学家对患者的复苏有了更好、更快和更准确的了解,并更成功地直接使用血液制品。然而,许多骨科医生——尽管进行了可能导致大量失血和术后凝血并发症的手术——却不知道 TEG 血液测试的存在及其提供的关键信息。提高骨科医生对 TEG 的认识可能会对肌肉骨骼护理的许多方面产生显著影响。

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