Suppr超能文献

通过体格检查和超声对腹主动脉瘤进行选择性筛查。

Selective screening for abdominal aortic aneurysms with physical examination and ultrasound.

作者信息

Lederle F A, Walker J M, Reinke D B

机构信息

Department of Medicine, Minneapolis Veterans Administration Medical Center, University of Minnesota 55417.

出版信息

Arch Intern Med. 1988 Aug;148(8):1753-6.

PMID:3041938
Abstract

Abdominal aortic aneurysm (AAA) is an important cause of preventable death in older persons. Persistently high rupture mortality rates indicate that these deaths can be prevented only by early detection and treatment of AAA. In an effort to develop an effective and efficient program of AAA detection, we selectively screened a high-risk population. Men aged 60 to 75 years with hypertension and/or coronary artery disease were randomly selected from a general medicine clinic and screened with physical examination and ultrasound. Eighteen previously unsuspected aneurysms, 3.6 to 5.9 cm in size (mean, 4.4 cm), were detected in 201 patients, for a prevalence of 9% (95% confidence interval: 4.7% to 13.3%). The specificity and positive predictive value of ultrasound were each 100%. Abdominal palpation detected only half of these aneurysms, but missed none in patients with an abdominal girth less than 100 cm (n = 6). This degree of sensitivity did not occur with "routine" examinations and requires that the examination be directed specifically toward AAA detection. We conclude that undiagnosed AAAs are common in this large subgroup of the clinic population, that ultrasound is an excellent screening test for AAAs, and that physical examination may be adequate for screening thin patients. We recommend that every two or three years persons over the age of 50 years undergo careful abdominal palpation aimed at detecting AAAs, as part of the periodic health examination. We further recommend that obese older men at high risk for AAA have at least one-time screening with abdominal ultrasound, regardless of findings on physical examination.

摘要

腹主动脉瘤(AAA)是老年人可预防死亡的重要原因。持续居高不下的破裂死亡率表明,只有通过早期发现和治疗AAA才能预防这些死亡。为了制定一个有效且高效的AAA检测方案,我们对高危人群进行了选择性筛查。从普通内科诊所中随机选取年龄在60至75岁之间患有高血压和/或冠状动脉疾病的男性,通过体格检查和超声进行筛查。在201名患者中检测出18个此前未被怀疑的动脉瘤,大小为3.6至5.9厘米(平均4.4厘米),患病率为9%(95%置信区间:4.7%至13.3%)。超声的特异性和阳性预测值均为100%。腹部触诊仅检测出这些动脉瘤的一半,但在腹围小于100厘米的患者(n = 6)中无一漏诊。这种敏感度在“常规”检查中并未出现,且要求检查专门针对AAA检测。我们得出结论,在这一庞大的临床人群亚组中,未被诊断出的AAA很常见,超声是AAA的优秀筛查检测方法,体格检查对于筛查体型较瘦的患者可能足够。我们建议50岁以上的人群每两到三年进行一次旨在检测AAA的仔细腹部触诊,作为定期健康检查的一部分。我们还建议,AAA高危的肥胖老年男性无论体格检查结果如何,至少进行一次腹部超声筛查。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验