Dumur Jean, Csajka Chantal, Pavec Ombeline, Messaoudi Siwar, Cretignier Titouan, Gaspar Frederic, Lang Pierre Olivier
Service de gériatrie et de réadaptation gériatrique, CHUV, 1011 Lausanne.
Service de pharmacie, CHUV, 1011 Lausanne.
Rev Med Suisse. 2018 Nov 7;14(626):2018-2023.
Sleep disorders are a recurrent complaint in geriatrics. Of multifactorial origin, they have a significant impact on health and quality of life. However, the answer is (too) often the prescription of benzodiazepines or related-drugs (Z-pills), sedative antidepressant, or another psychotropic medication. More recently, melatonin, valerian and, in Switzerland, clomethiazol are widely considered as effective and more suitable alternatives for aged people. We present a systematic review of the literature on the efficacy and tolerance of these molecules, of which the main objective is to demonstrate that non-pharmacological approach must remain the first-line therapy of insomnia in geriatrics.
睡眠障碍是老年医学中反复出现的问题。其病因是多因素的,对健康和生活质量有重大影响。然而,答案往往是(过度)开具苯二氮䓬类药物或相关药物(助眠药)、镇静性抗抑郁药或其他精神药物。最近,褪黑素、缬草,以及在瑞士的氯美噻唑,被广泛认为是对老年人有效的且更合适的替代品。我们对这些药物的疗效和耐受性进行了文献系统综述,其主要目的是证明非药物方法必须仍然是老年失眠症的一线治疗方法。