乙型肝炎疫苗可诱导女性生殖道黏膜抗体应答，提示其具有潜在的抗感染保护机制。
Hepatitis B Vaccination Induces Mucosal Antibody Responses in the Female Genital Tract, Indicating Potential Mechanisms of Protection Against Infection.
机构信息
From the Centre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, United Kingdom.
出版信息
Sex Transm Dis. 2019 May;46(5):e53-e56. doi: 10.1097/OLQ.0000000000000949.
PMID:30444798
Abstract
Vaccines against hepatitis B virus confer effective protection. Enzyme-linked immunosorbent assay was developed to test for specific antibodies in female genital tract secretions. Anti-hepatitis B IgG and IgA were detected in the cervicovaginal secretions of women after hepatitis B vaccination, indicating a potential genital tract role for neutralizing antibodies against sexually transmitted hepatitis B virus.
摘要
乙肝病毒疫苗可提供有效保护。酶联免疫吸附试验被开发用于检测女性生殖道分泌物中的特异性抗体。乙肝疫苗接种后，在女性宫颈阴道分泌物中检测到抗乙肝 IgG 和 IgA，表明针对性传播乙肝病毒的中和抗体可能在生殖道中发挥作用。
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