Tournier M, Pariente A, Bégaud B, Bénard-Laribière A
Université Bordeaux, Inserm, Bordeaux Population Health Research Center, Pharmacoepidemiology research team, UMR 1219, 33000 Bordeaux, France; Centre hospitalier Charles-Perrens, 33000 Bordeaux, France; DRUGS-SAFE National Platform of Pharmacoepidemiology, France.
Université Bordeaux, Inserm, Bordeaux Population Health Research Center, Pharmacoepidemiology research team, UMR 1219, 33000 Bordeaux, France; Centre hospitalier universitaire de Bordeaux, 33000 Bordeaux, France; DRUGS-SAFE National Platform of Pharmacoepidemiology, France.
Presse Med. 2018 Oct;47(10):882-885. doi: 10.1016/j.lpm.2018.10.004. Epub 2018 Oct 25.
Among 8 countries included in the report of ANSM, France is second behind Spain, when defined daily doses (DDD) are considered. Few studies, recent and based on representative samples of population, investigated the use of benzodiazepines in other countries and data are limited to compare France and other countries. In most countries, the use of benzodiazepines increases with age and is more frequent in women than in men. Variations of benzodiazepines use that were observed in other countries are similar to those observed in France, with a slight decrease but persistent high levels of use. In most countries, the long-term use of benzodiazepines is stable over time even though simple use decreases.
在法国国家药品安全局(ANSM)报告所涵盖的8个国家中,若按限定日剂量(DDD)计算,法国仅次于西班牙。近期针对其他国家具有代表性人群样本开展的研究较少,用于比较法国与其他国家的苯二氮䓬类药物使用数据有限。在大多数国家,苯二氮䓬类药物的使用随年龄增长而增加,且女性使用频率高于男性。在其他国家观察到的苯二氮䓬类药物使用变化与在法国观察到的相似,虽有轻微下降但使用水平仍持续较高。在大多数国家,尽管单纯使用量有所下降,但苯二氮䓬类药物的长期使用随时间保持稳定。