Wu Zhuoxia, Xing Yunlong, Liu Xin, Chen Wanying, Kong Jiao, Wu Ronghui, Zhang Lianbo
Department of Plastic and Reconstructive Surgery.
Department of Stomatology, China-Japan Union Hospital of Jilin University, Changchun, China.
Medicine (Baltimore). 2018 Nov;97(47):e13186. doi: 10.1097/MD.0000000000013186.
Ossifying fibroma (OF) is a benign fibro-osseous lesion that can develop in the oral and maxillofacial region. OF is more common in females and has a marked predilection for the mandible, occurring rarely in the maxilla. Lesions grow slowly and are usually asymptomatic until growth produces an obvious swelling, pain, paresthesia, and facial deformity. With low rates of recurrence, treatment is usually curettage or resection. Very large lesions that invade other organs and that cannot be completely removed should be excised conservatively.
We present a case of a 46-year-old female with a very large fibro-osseous lesion arising from the maxilla who was more concerned about the facial appearance and requested conservative treatment for economic reasons.
The pathological results based on conservative excision of the lesion confirmed the diagnosis of OF.
We chose conservative excision via the Weber-Ferguson approach and followed up every 6 months. Facial deformity correction was performed 2 years postoperatively and right lower eyelid ectropion correction 3 years after the primary excision.
The ectropion deformity in the right lower eyelid improved dramatically with a better facial appearance and no obvious swelling.
Treatment programs for OF should be individualized based on the size, growth rate, invasion, and interference with facial function and esthetics. If lesions grow slowly, we suppose that it is feasible to excise conservatively when reconstruction cannot be performed due to esthetic and functional problems. Also regular postoperative follow-up is necessary to detect recurrence, and to improve facial appearance as required.
骨化性纤维瘤(OF)是一种可发生于口腔颌面部的良性纤维骨性病变。OF在女性中更为常见,明显好发于下颌骨,在上颌骨中很少发生。病变生长缓慢,通常无症状,直到生长导致明显肿胀、疼痛、感觉异常和面部畸形。由于复发率低,治疗通常采用刮除术或切除术。对于侵犯其他器官且无法完全切除的非常大的病变,应进行保守切除。
我们报告一例46岁女性,上颌骨出现一个非常大的纤维骨性病变,患者更关注面部外观,因经济原因要求保守治疗。
基于病变保守切除的病理结果确诊为OF。
我们选择经Weber-Ferguson入路进行保守切除,并每6个月随访一次。术后2年进行面部畸形矫正,初次切除后3年进行右下睑外翻矫正。
右下睑外翻畸形明显改善,面部外观更好,无明显肿胀。
OF的治疗方案应根据病变大小、生长速度、侵犯情况以及对面部功能和美观的影响进行个体化制定。如果病变生长缓慢,我们认为当由于美观和功能问题无法进行重建时,保守切除是可行的。此外,术后定期随访对于检测复发以及根据需要改善面部外观是必要的。