Astex Pharmaceuticals , 436 Cambridge Science Park, Milton Road , Cambridge CB4 0QA , United Kingdom.
Carmot Therapeutics Inc. , 740 Heinz Avenue , Berkeley , California 94710 , United States.
J Med Chem. 2019 Apr 25;62(8):3857-3872. doi: 10.1021/acs.jmedchem.8b01472. Epub 2018 Nov 21.
This Miniperspective is the third in a series reviewing fragment-to-lead publications from a given year. Following our reviews for 2015 and 2016, this Miniperspective provides tabulated summaries of relevant articles published in 2017 along with some general observations. In addition, we discuss insights obtained from analysis of the combined data set of 85 examples from all three years of publications.
这篇小综述是对给定年份的片段到先导出版物进行综述的系列文章中的第三篇。继我们对 2015 年和 2016 年的综述之后，本篇小综述提供了 2017 年相关文章的表格摘要，并提出了一些一般性观察结果。此外，我们还讨论了从对来自三年出版物的 85 个实例的综合数据集的分析中获得的见解。
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