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在应对脑膜炎 B 型疫情时,实施基于大学的大规模免疫接种计划的经验。

Experience implementing a university-based mass immunization program in response to a meningococcal B outbreak.

机构信息

a Vaccines US Medical Affairs , Pfizer Inc , Collegeville , PA , USA.

b Emergency Management & Continuity, University of Oregon , Eugene , OR , USA.

出版信息

Hum Vaccin Immunother. 2019;15(3):717-724. doi: 10.1080/21645515.2018.1547606. Epub 2019 Jan 8.

DOI:10.1080/21645515.2018.1547606
PMID:30462563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6988882/
Abstract

Neisseria meningitidis serogroup B (MenB) has caused several recent outbreaks of meningococcal disease on US college campuses. In January 2015, a case of MenB was reported at a university in Oregon, culminating in an outbreak with a total of 7 cases (including 1 fatality) identified over a 5-month period. In response to the outbreak, the university organized a mass immunization campaign with 4 "opt-in" immunization clinics. The preparation, challenges, and resources required for organization and implementation of a mass immunization program in response to an outbreak at a large public university are discussed herein. Based on the logistical challenges as well as resource expenditures associated with planning and executing a mass immunization effort, this experience illustrates that proactive, routine immunization of incoming students is the best strategy for MenB outbreak prevention.

摘要

脑膜炎奈瑟菌 B 群(MenB)在美国大学校园引发了几起近期的脑膜炎球菌病暴发。2015 年 1 月,俄勒冈州一所大学报告了一例 MenB 病例,最终导致在 5 个月内共发现 7 例(包括 1 例死亡)病例。针对此次暴发,该校组织了一次大规模免疫接种活动,共设有 4 个“选择加入”免疫接种诊所。本文讨论了针对大型公立大学暴发疫情组织和实施大规模免疫接种计划所需的准备、挑战和资源。根据与规划和实施大规模免疫接种工作相关的后勤挑战和资源支出,这一经验表明,针对 MenB 暴发的主动、常规对入学新生进行免疫接种是最佳策略。

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