Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA.
Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA.
Immunity. 2018 Nov 20;49(5):793-795. doi: 10.1016/j.immuni.2018.11.007.
The diversity of natural killer cells between mouse and human is poorly understood. In this issue of Immunity, Crinier et al. (2018) utilize single-cell RNA-seq to profile splenic and blood NK cells from both organisms, uncovering both tissue- and species-specific transcriptomic signatures.
鼠类和人类自然杀伤细胞的多样性尚未得到充分了解。在本期《免疫》杂志上,Crinier 等人(2018)利用单细胞 RNA 测序技术对来自这两种生物的脾和血液 NK 细胞进行了分析,揭示了组织和物种特异性的转录组特征。