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内耳平衡器官及其传导通路的疾病。

Disorders of the inner-ear balance organs and their pathways.

作者信息

Young Allison S, Rosengren Sally M, Welgampola Miriam S

机构信息

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia.

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia.

出版信息

Handb Clin Neurol. 2018;159:385-401. doi: 10.1016/B978-0-444-63916-5.00025-2.

Abstract

Disorders of the inner-ear balance organs can be grouped by their manner of presentation into acute, episodic, or chronic vestibular syndromes. A sudden unilateral vestibular injury produces severe vertigo, nausea, and imbalance lasting days, known as the acute vestibular syndrome (AVS). A bedside head impulse and oculomotor examination helps separate vestibular neuritis, the more common and innocuous cause of AVS, from stroke. Benign positional vertigo, a common cause of episodic positional vertigo, occurs when otoconia overlying the otolith membrane falls into the semicircular canals, producing brief spells of spinning vertigo triggered by head movement. Benign positional vertigo is diagnosed by a positional test, which triggers paroxysmal positional nystagmus in the plane of the affected semicircular canal. Episodic spontaneous vertigo caused by vestibular migraine and Ménière's disease can sometimes prove hard to separate. Typically, Ménière's disease is associated with spinning vertigo lasting hours, aural fullness, tinnitus, and fluctuating hearing loss while VM can produce spinning, rocking, or tilting sensations and light-headedness lasting minutes to days, sometimes but not always associated with migraine headaches or photophobia. Injury to both vestibular end-organs results in ataxia and oscillopsia rather than vertigo. Head impulse testing, dynamic visual acuity, and matted Romberg tests are abnormal while conventional neurologic assessments are normal. A defect in the bony roof overlying the superior semicircular canal produces vertigo and oscillopsia provoked by loud sound and pressure (when coughing or sneezing). Three-dimensional temporal bone computed tomography scan and vestibular evoked myogenic potential testing help confirm the diagnosis of superior canal dehiscence. Collectively, these clinical syndromes account for a large proportion of dizzy and unbalanced patients.

摘要

内耳平衡器官疾病可根据其临床表现方式分为急性、发作性或慢性前庭综合征。突然的单侧前庭损伤会导致严重眩晕、恶心和持续数天的失衡,这被称为急性前庭综合征(AVS)。床边头部脉冲和动眼神经检查有助于将AVS更常见且无害的病因——前庭神经炎与中风区分开来。良性阵发性位置性眩晕是发作性位置性眩晕的常见病因,当覆盖耳石膜的耳石落入半规管时就会发生,头部运动可引发短暂的旋转性眩晕发作。良性阵发性位置性眩晕通过位置试验进行诊断,该试验会在受影响半规管平面引发阵发性位置性眼球震颤。由前庭性偏头痛和梅尼埃病引起的发作性自发性眩晕有时很难区分。通常,梅尼埃病与持续数小时的旋转性眩晕、耳胀满感、耳鸣和波动性听力损失有关,而前庭性偏头痛可产生旋转、摇晃或倾斜感以及持续数分钟至数天的头晕,有时但并非总是与偏头痛性头痛或畏光有关。双侧前庭终器损伤会导致共济失调和视振荡,而非眩晕。头部脉冲测试、动态视力和改良罗姆伯格测试结果异常,而传统神经学评估结果正常。覆盖上半规管的骨顶缺陷会因大声响和压力(咳嗽或打喷嚏时)引发眩晕和视振荡。三维颞骨计算机断层扫描和前庭诱发肌源性电位测试有助于确诊上半规管裂。总体而言,这些临床综合征在头晕和失衡患者中占很大比例。

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