Muneer Tazeen, Tariq Aisha, Siddiqui Asif H, Amanullah Muneer
Emergency Medicine, Glangwili General Hospital, Carmarthen, GBR.
Miscellaneous, The Aga Khan University Hospital, Karachi, PAK.
Cureus. 2018 Sep 24;10(9):e3348. doi: 10.7759/cureus.3348.
Pheochromocytoma is a rare benign tumor of the adrenal gland. A select few cases may be malignant, and metastatic cases are exceedingly rare. It often presents with symptoms of catecholamine excess, such as sweating, palpitations, headaches, and characteristic paroxysmal hypertension. Due to its diffuse symptoms, it is difficult to diagnose and is often diagnosed late. We describe the unique case of a 44-year-old female patient who presented with uncontrolled hypertension and vomiting, accompanied by lower back pain. She was diagnosed with malignant pheochromocytoma with multiple metastases to the lungs, vertebrae, scapulae, and skull. Because of the advanced state of her disease, the patient was started on treatment with the chemotherapeutic combination of cyclophosphamide, vincristine, and dacarbazine. However, she had a complicated hospital course and died because of aspiration pneumonia and sepsis.
嗜铬细胞瘤是一种罕见的肾上腺良性肿瘤。极少数病例可能为恶性，而转移性病例极为罕见。它常表现为儿茶酚胺过量的症状，如出汗、心悸、头痛以及特征性的阵发性高血压。由于其症状多样，难以诊断，且常常诊断较晚。我们描述了一位44岁女性患者的独特病例，该患者出现难以控制的高血压和呕吐，并伴有下背部疼痛。她被诊断为恶性嗜铬细胞瘤，伴有肺部、椎骨、肩胛骨和颅骨的多处转移。由于病情处于晚期，患者开始接受环磷酰胺、长春新碱和达卡巴嗪联合化疗。然而，她的住院过程复杂，最终因吸入性肺炎和败血症死亡。
