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用于心脏性猝死一级预防的植入式心律转复除颤器患者的室性心动过速预测

Ventricular tachycardia prediction in patients with implantable cardioverter-defibrillators for primary prevention of sudden cardiac death.

作者信息

Lebedeva Viktoria K, Klitcenko Olga A, Lebedev Dmitry S, Lyubimtseva Tamara A

机构信息

Arrhythmology Department, National Almazov Medical Research Centre, 2 Akkuratova St., St. Petersburg, 197341, Russian Federation.

North-Western State Medical University Named After I.I Mechnikov., 41 Kirochnaya St., St. Petersburg, 191015, Russian Federation.

出版信息

Indian Pacing Electrophysiol J. 2019 Mar-Apr;19(2):57-62. doi: 10.1016/j.ipej.2018.11.011. Epub 2018 Nov 25.

Abstract

Clinical data analysis of 83 patients with implantable cardioverter-defibrillators (ICDs) for sudden cardiac death (SCD) primary prevention has been done. We revealed 5 parameters associated with the detection of life-threatening ventricular arrhythmias. These parameters formed the basis for constructing a logistic regression model. The model makes it possible to obtain the probability of occurrence of a specific event depending on the severity of the predictive parameters and the degree of its influence (risk of true ventricular arrhythmias detection). Estimating the potential risk of the life-threatening arrhythmias, individual programming options are required in implantable cardioverter-defibrillators (ICDs) to reduce the amount of unnecessary electrotherapy, as well as more accurate monitoring of the patient's drug therapy.

摘要

对83例植入式心脏复律除颤器(ICD)用于心脏性猝死(SCD)一级预防的患者进行了临床数据分析。我们发现了5个与危及生命的室性心律失常检测相关的参数。这些参数构成了构建逻辑回归模型的基础。该模型能够根据预测参数的严重程度及其影响程度(检测真正室性心律失常的风险)获得特定事件发生的概率。为了估计危及生命的心律失常的潜在风险,植入式心脏复律除颤器(ICD)需要采用个体化编程选项,以减少不必要的电治疗次数,并更准确地监测患者的药物治疗情况。

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