Spedali Civili di Brescia, Brescia, Italy.
Department of Interventional Pneumology, Careggi University Hospital, Florence, Italy -
Panminerva Med. 2019 Sep;61(3):401-421. doi: 10.23736/S0031-0808.18.03571-1. Epub 2018 Nov 27.
Bronchoscopic lung volume reduction (BLVR) has been proven to be effective in patients with severe emphysema. These techniques are divided into two groups: non-blocking devices that are independent of collateral ventilation and blocking devices that are dependent on collateral ventilation so the choice of the target lobe with inadequate scissors is crucial for the success of the treatment. Current evidences suggest that not all classes and phenotypes of emphysema will benefit from BLVR, and that each technique appears to provide a greater benefit to specific sub-groups of patients. Careful patient selection is imperative to prevent insertion in patients unlikely to gain clinical benefits as well as wasteful expenditure. The Chartis system represents the gold standard for measuring fissure integrity and is a direct measurement method. Indirect method is instead the TC study which, thanks to the development of software for quantitative analysis, allows us to obtain reliable measurements of regional density of parenchyma, airway thickness and scissor integrity. BLVR is a highly complex procedure: a first-level competence is a pre-requisite for admission to training. The practical training must be based on discussion of clinical cases and the insertion techniques of the different devices on plastic or animal models, or on cadavers. A specific course, offering final certification, has been developed on the use of Zephyr valves.
支气管镜肺减容术(BLVR)已被证明对严重肺气肿患者有效。这些技术分为两组:不依赖侧支通气的非阻塞性装置和依赖侧支通气的阻塞性装置,因此选择剪刀不足的目标肺叶对于治疗的成功至关重要。目前的证据表明,并非所有类别的肺气肿和表型都将从 BLVR 中受益,而且每种技术似乎都为特定的亚组患者提供了更大的益处。为了防止将不太可能获得临床益处的患者插入以及浪费开支,必须进行仔细的患者选择。Chartis 系统是测量裂隙完整性的金标准,是一种直接测量方法。间接方法是 TC 研究,由于用于定量分析的软件的发展,该方法允许我们获得区域实质密度、气道厚度和剪刀完整性的可靠测量。BLVR 是一个非常复杂的过程:一级能力是接受培训的先决条件。实践培训必须基于对不同装置的临床病例和插入技术的讨论,这些装置可以是在塑料或动物模型上,也可以是在尸体上进行。已经开发了关于使用 Zephyr 阀的特定课程,提供最终认证。