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肾结石二期经皮肾镜取石术的治疗效果——单中心经验

Outcomes of second-look percutaneous nephrolithotomy in renal calculi-a single centre experience.

作者信息

Kumar Sumit, Karthikeyan Vilvapathy Senguttuvan, Mallya Ashwin, Keshavamurthy Ramaiah

机构信息

Institute of Nephro Urology, Bangalore, India.

出版信息

Turk J Urol. 2018 Sep;44(5):406-410. doi: 10.5152/tud.2018.76299. Epub 2018 Sep 1.

Abstract

OBJECTIVE

Percutaneous nephrolithotomy (PCNL) carries significant potential for morbidity. Scant data exists on indications and outcomes of second-look PCNL after a failure to completely clear renal stones at the first attempt. We present our experience with second-look PCNL.

MATERIAL AND METHODS

This was a retrospective record review of 922 patients who underwent unilateral PCNL at a tertiary care center in South India. Baseline patient, stone characteristics and outcomes were compared between 844 patients undergoing primary PCNL and 78 patients requiring second-look PCNL.

RESULTS

Increased stone complexity in terms of Guy stone score (GSS), stone size, staghorn calculi and stones in multiple locations were significantly associated with primary treatment failure (p<0.001). Operative time >75 min had a significant association with need for second-look PCNL and complications. Initial PCNL was discontinued due to bleeding (28; 35.9%), pelvicalyceal system perforation (3; 3.9%) and purulent urine leading to urosepsis and hemodynamic instability (2; 2.6%). Staged PCNL was done in 44 (56.3%) patients. During second-look PCNL, new access tracts were necessary in majority (42; 53.9%) of the patients and multiple tracts in 20 (25.6%) patients. In second-look PCNL, complications were comparable to primary PCNL (p=0.289).

CONCLUSION

Second-look PCNL should be advocated in patients where the initial PCNL was discontinued due to bleeding, perforation of collecting system, prolonged operative time (>75 min) and in patients with large stone burden.

摘要

目的

经皮肾镜取石术(PCNL)有较高的发病风险。关于首次尝试未能完全清除肾结石后二期PCNL的适应证和结果的数据较少。我们介绍我们在二期PCNL方面的经验。

材料与方法

这是一项对在印度南部一家三级医疗中心接受单侧PCNL的922例患者的回顾性记录研究。比较了844例行一期PCNL的患者和78例需要二期PCNL的患者的基线患者、结石特征及结果。

结果

根据盖伊结石评分(GSS)、结石大小、鹿角形结石和多部位结石判断,结石复杂性增加与一期治疗失败显著相关(p<0.001)。手术时间>75分钟与二期PCNL的需求及并发症显著相关。一期PCNL因出血(28例;35.9%)、肾盂肾盏系统穿孔(3例;3.9%)以及脓性尿液导致尿脓毒症和血流动力学不稳定(2例;2.6%)而中断。44例(56.3%)患者进行了分期PCNL。在二期PCNL期间,大多数患者(42例;53.9%)需要新的穿刺通道,20例(25.6%)患者需要多个通道。在二期PCNL中,并发症与一期PCNL相当(p=0.289)。

结论

对于因出血、集合系统穿孔、手术时间延长(>75分钟)以及结石负荷大而中断一期PCNL的患者,应提倡二期PCNL。

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